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Over onsWaar vindt u onsA. (Ali) Saber Hosseinabadi, PhD

A. Saber Hosseinabadi, PhD

Postdoctoral researcher

WORK EXPERIENCE

Title

Date

Institute

Postdoctoral researcher

2017 - Now

University of Groningen, Netherlands

Postdoctoral researcher

2016 - 2016

UMCG, Netherlands

EDUCATION

Title

Date

Institute

PhD in Cancer genetics & genomics

2011 - 2016

UMCG, Netherlands

MSc. in Genetics

2006 - 2009

University Putra Malaysia (UPM), Malaysia

BSc. in Cellular & molecular biology

2000 - 2004

Tonekabon Azad University, Iran

PUBLICATIONS

·       Wei J, van der Wekken AJ, Saber A, Terpsta MM, Schuuring E, Timens W, Hiltermann TJN, Groen HJM, van den Berg A, Kok K. Mutations in EMT-related genes in ALK positive, crizotinib resistant, non-small cell lung cancers. Cancers. 2018. Accepted.

·       van der Wekken AJ, Kuiper JL, Saber A, Terpstra MM, Wei J, Hiltermann TJN, Thunnissen E, Heideman DAM, Timens W, Schuuring E, Kok K, Smit EF, van den Berg A, Groen HJM. Overall survival in EGFR mutated non-small-cell lung cancer patients treated with afatinib after EGFR TKI and resistant mechanisms upon disease progression. PLoS ONE. 2017; 12(8): e0182885.

·       Ferronika P, van den Bos H, Spierings DCJ, Taudt A, Saber A, Hiltermann TJN, Kok K, Porubsky D, van der Wekken AJ, Timens W, Foijer F, Tatché MC, Groen HJM, Lansdorp PM, van den Berg A. Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small cell lung cancer patient. Annals of Oncology. 2017; 28(7): 1668-1670.

·       Saber A, Hiltermann TJN, Kok K, Terpstra MM, de Lange K, Timens W, Groen HJM, van den Berg A. Mutation patterns in small cell and non-small cell lung cancer patients suggest a different level of heterogeneity between primary and metastatic tumors. Carcinogenesis. 2017; 38(2): 144-151.

·       Saber A, van der Wekken AJ, Kok K, Terpstra MM, Bosman LJ, Mastik MF, Timens W, Schuuring E, Hiltermann TJN, Groen HJM, van den Berg A. Genomic aberrations in crizotinib resistant lung adenocarcinoma samples by transcriptome sequencing. PLoS ONE. 2016; 11(4): e0153065.

·       Saber A, van der Wekken AJ, Kerner GSMA, van den Berge M, Timens W, Schuuring E, ter Elst A, van den Berg A, Hiltermann TJN, Groen HJM. Chronic obstructive pulmonary disease is not associated with KRAS mutations in non-small cell lung cancer. PLoS ONE. 2016; 11(3): e0152317.

·       van der Wekken AJ, Saber A, Hiltermann TJN, Kok K, van den Berg A, Groen HJM. Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature. Critical Reviews in Oncology/Hematology. 2016; 100: 107-116.

·       Saber A, van der Wekken AJ, Hiltermann TJN, Kok K, van den Berg A, Groen HJM. Genomic aberrations guiding treatment of non-small cell lung cancer patients. Cancer Treatment Communications. 2015; 4: 23-33.

·       Liu Y, Abdul Razak FR, Terpstra M, Chan FC, Saber A, Nijland M, van Imhoff G, Visser L, Gascoyne R, Steidl C, Kluiver J, Diepstra A, Kok K, van den Berg A. The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing. Leukemia. 2014; 28: 2248-2251.

 

CONFERENCES

·       Wei J, Rybczynska AA, van der Wekken A, Saber A, Terpstra MM, et al. All-in-one RNA-based assay to detect therapeutic biomarkers in lung cancer. 3rd molecular analysis for personalized therapy; 2017 Oct 13-14; Zurich, Switzerland.

·       Spierings D, van den Bos H, Ferronika P, Saber A, Hiltermann TJN, et al. Intra-tumor heterogeneity in small cell lung cancer assessed by single-cell whole genome sequencing. Single cell biology conference; 2016 Mar 8-10; Cambridge, UK.

·       Saber A, Kok K, Terpstra MM, Timens W, Aukema S, et al. Whole exome sequencing reveals a distinct mutation pattern in metastatic small cell lung cancer compared to non-small cell lung cancer. 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, US.

·       Saber A, van der Wekken A, Kok K, Terpstra MM, Mastik MF, et al. Detection of fusion genes in lung cancer biopsies of crizotinib resistant patients. 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, US.

·       Saber A, Kok K, Terpstra MM, Timens W, Aukema S, et al. Clonal relation between primary lung cancer and metastases assessed by whole exome sequencing. 2nd annual meeting of the cancer research center groningen, 2014 Oct 31, Groningen, The Netherlands.

·       Hooi LO, Loo LW, Johari MA, Saber A. Report of a rare case of Vitamin D-Dependent Rickets Type II. Asia pacific paediatric endocrinology society (APPES) 6th biennial scientific meeting; 2010 Nov 17-20, Xian, China.

 

LANGUAGE SKILLS

English

Fluent

Persian

Native language

Dutch

Limited working proficiency

Last modified:08 October 2018 9.10 p.m.

Contactgegevens

UMCG

Functie:
Postdoctoraal onderzoeker
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