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Practical matters How to find us A.S.S. (Alexander) Dömling, Prof Dr

A.S.S. (Alexander) Dömling, Prof Dr

Professor and chair Drug Design Group

A.S.S. (Alexander) Dömling, Prof Dr

Faculty of Science and Engineering

Telephone:

+31 50 36 33307

+31 50 36 33336 (secretariat)

+31 50 36 37582 (fax)

E-mail:

a.s.s.domling rug.nl

Homepage ORCID Research Portal

Publications

Enabling large-scale design, synthesis and validation of small molecule protein-protein antagonists

Koes, D. , Khoury, K. , Huang, Y. , Wang, W. , Bista, M. , Popowicz, G. M. , Wolf, S. , Holak, T. A. , Dömling, A. & Camacho, C. J. , 12-Mar-2012 , In: PLoS ONE. 7 , 3 , 8 p. , e32839.

Research output: Contribution to journal › Article › Academic › peer-review

Chemistry and Biology Of Multicomponent Reactions

Domling, A. , Wang, W. & Wang, K. , Jun-2012 , In: Chemical reviews. 112 , 6 , p. 3083-3135 53 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Efficient Assembly of Iminodicarboxamides by a "Truly" Four-Component Reaction

Khoury, K. , Sinha, M. K. , Nagashima, T. , Herdtweck, E. & Domling, A. , 2012 , In: Angewandte Chemie-International Edition. 51 , 41 , p. 10280-10283 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

Shaabani, S. , Gadina, L. , Surmiak, E. , Wang, Z. , Zhang, B. , Butera, R. , Zarganes-Tzitzikas, T. , Rodriguez, I. , Kocik-Krol, J. , Magiera-Mularz, K. , Skalniak, L. , Dömling, A. & Holak, T. A. , 2022 , In: Molecules. 27 , 11 , 17 p. , 3454.

Research output: Contribution to journal › Article › Academic › peer-review

Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders

Ulgheri, F. , Spanu, P. , Deligia, F. , Loriga, G. , Fuggetta, M. P. , de Haan, I. , Chandgudge, A. , Groves, M. & Domling, A. , 5-Feb-2022 , In: European Journal of Medicinal Chemistry. 229 , 114002.

Research output: Contribution to journal › Article › Academic › peer-review

Dibenzothiazepine Based MCR Chemistry

Lei, X. , Angeli, G. , Dömling, A. & Neochoritis, C. G. , 25-May-2022 , In: European Journal of Organic Chemistry. 2022 , 20 , 5 p. , e202200220.

Research output: Contribution to journal › Article › Academic › peer-review

Discovery of chromene compounds as inhibitors of PvdQ acylase of Pseudomonas aeruginosa

Vogel, J. G. T. , Wibowo, J. P. , Fan, H. , Setroikromo, R. , Wang, K. , Dömling, A. , Dekker, F. J. & Quax, W. J. , 13-Jun-2022 , (E-pub ahead of print) In: Microbes and infection. 29 p. , 105017.

Research output: Contribution to journal › Article › Academic › peer-review

Fluorene-Based Multicomponent Reactions

Lei, X. , Thomaidi, M. , Angeli, G. K. , Dömling, A. & Neochoritis, C. G. , 1-Jan-2022 , In: Synlett. 33 , 2 , p. 155-160 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Highly Stereoselective Ugi/Pictet-Spengler Sequence

Zhang, B. , Kurpiewska, K. & Dömling, A. , 12-May-2022 , (E-pub ahead of print) In: The Journal of Organic Chemistry.

Research output: Contribution to journal › Article › Academic › peer-review

Nanoporous Gold Catalyst for the Oxidative N-Dealkylation of Drug Molecules: A Method for Synthesis of N-Dealkylated Metabolites

Alipour Najmi, A. , Jafariyeh-Yazdi, E. , Hadian, M. , Hermans, J. , Bischoff, R. , Yue, J. , Dömling, A. , Wittstock, A. & Permentier, H. P. , 3-Jun-2022 , In: ChemMedChem. 17 , 11 , 4 p. , e202200040.

Research output: Contribution to journal › Article › Academic › peer-review

All (362) publications

Press/media

Merck’s Covid Pill Fumble Gives Pfizer Potential $17 Billion Win

Alex Dömling

03/02/2022

Press/Media: Research › Popular

Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale

Alex Dömling

29/08/2019

Press/Media: Research › Academic

Computational chemistry, Medicijnen & Farmacologie, Organische chemie

Alex Dömling

26/07/2019

Press/Media: Research › Academic

Supersnelle boorzuurchemie dankzij syntheserobot

Alex Dömling

26/07/2019

Press/Media: Research › Academic

Supersnelle boorzuurchemie dankzij syntheserobot

Alex Dömling

26/07/2019

Press/Media: Research › Academic

Snelle methode voor synthese van kandidaat-geneesmiddelen. High-throughput systeem levert mogelijk middel tegen tuberculose op

Alex Dömling

09/07/2019

Press/Media: Research › Academic

Small-volume, high-throughput organic synthesis. New method synthesizes and evaluates large number of drug leads

Alex Dömling

09/07/2019

Press/Media: Research › Academic

Acoustic robot races through chemical reactions

Alexander Dömling

11/03/2019

Press/Media: Research › Professional

Acoustic robot races through chemical reactions. Using ultrasound to dispense reagents could accelerate the development of synthetic methods for drug discovery

Alex Dömling

11/03/2019

Press/Media: Research › Academic

Bedumer Winterloop 2016

Alex Dömling

06/02/2016

Press/Media: Public Engagement Activities › Popular

All (11) press/media

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