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About us Practical matters How to find us A.M. Sabogal Guaqueta, MSc

Research interests

My research interest focuses on the research of molecular mechanisms underlying cerebrovascular diseases, aging processes, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. I investigated the role of statins and various natural products, including linalool, as potential neuroprotective agents in neurodegenerative diseases. Lately, my focus has shifted towards delving into mitochondrial metabolism and its link to inflammation in the context of neurodegenerative diseases, particularly the generation and characterization of human microglia derived from induced pluripotent stem cells of Parkinson's disease patients. I am greatly interested in expanding my research in understanding neuroinflammation as a key factor in neurodegenerative diseases.


Mitochondrial transplantation rescues neuronal cells from ferroptosis

Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction

The importance of microglia in metabolic changes in the brain: A world to explore

Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies

Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity

The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids

Mitochondrial dysfunction in neurodegenerative diseases: A focus on iPSC-derived neuronal models

Microglia alterations in neurodegenerative diseases and their modeling with human induced pluripotent stem cell and other platforms

Unraveling molecular signaling in neurodegenerative diseases: focus on a protective mechanism mediated by linalool

Linalool attenuates oxidative stress and mitochondrial dysfunction mediated by glutamate and NMDA toxicity

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