prof. dr. A. (Arjan) Kortholt

associate professor

Research

Research units:

Postal address:
Nijenborgh
7
Gebouw 5172, ruimte 0536
Groningen
Netherlands
Phone: +31 50 363 4206Fax: +31 50 363 2368
  1. 2019
  2. Deyaert, E., Leemans, M., Singh, R. K., Gallardo, R., Steyaert, J., Kortholt, A., ... Versées, W. (2019). Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein. Biochemical Journal, 476(1), 51-66. https://doi.org/10.1042/BCJ20180803
  3. 2018
  4. 2017
  5. Deyaert, E., Wauters, L., Guaitoli, G., Konijnenberg, A., Leemans, M., Terheyden, S., ... Versées, W. (2017). A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nature Communications, 8(1), 1-12. [1008]. https://doi.org/10.1038/s41467-017-01103-4
  6. 2016
  7. Skoge, M., Wong, E., Hamza, B., Bae, A., Martel, J., Kataria, R., ... Irimia, D. (2016). A Worldwide Competition to Compare the Speed and Chemotactic Accuracy of Neutrophil-Like Cells. PLoS ONE, 11(6), [e0154491]. https://doi.org/10.1371/journal.pone.0154491
  8. Khanna, A., Lotfi, P., Chavan, A. J., Montaño, N. M., Bolourani, P., Weeks, G., ... Charest, P. G. (2016). The small GTPases Ras and Rap1 bind to and control TORC2 activity. Scientific Reports, 6, 1-9. [25823]. https://doi.org/10.1038/srep25823
  9. 2015
  10. Gilsbach, B. K., Messias, A. C., Ito, G., Sattler, M., Alessi, D. R., Wittinghofer, A., & Kortholt, A. (2015). Structural Characterization of LRRK2 Inhibitors. Journal of Medicinal Chemistry, 58(9), 3751−3756. https://doi.org/10.1021/jm5018779
  11. Wu, J., Pipathsouk, A., Keizer-Gunnink, A., Fusetti, F., Alkema, W., Liu, S., ... Weiner, O. D. (2015). Homer3 regulates the establishment of neutrophil polarity. Molecular Biology of the Cell, 26(9), 1629-1639. https://doi.org/10.1091/mbc.E14-07-1197
  12. Terheyden, S., Ho, F. Y., Gilsbach, B. K., Wittinghofer, A., & Kortholt, A. (2015). Revisiting the Roco G-protein cycle. Biochemical Journal, 465(1), 139-147. https://doi.org/10.1042/BJ20141095
  13. 2014
  14. 2013
  15. 2012
  16. 2011
  17. 2010
  18. 2008
  19. 2007
  20. 2006
  21. 2003
  22. Blaauw, M., Knol, JC., Kortholt, A., Roelofs, J., Ruchira, N. V., Postma, M., ... Visser, A. J. W. G. (2003). Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins. EMBO Journal, 22(19), 5047-5057. https://doi.org/10.1093/emboj/cdg508

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