Lecture Aleksei Aksimentiev
|11 July 2012||FWN-Building 5111.0080, Nijenborgh 4, 9747 AG, Groningen|
|Speaker:||Prof. Dr. Aleksei Aksimentiev|
|Affiliation:||University of Illinois, Urbana-Champaign, USA|
|Title:||Molecular mechanics of nucleid acids: DNA condensation, replication and nanopore sequencing|
|Date:||Wed Jul 11, 2012|
|Telephone:||+31 50 363 4323|
After water and oxygen, DNA is, very likely, the most famous molecule of life known to men. This is not surprising, as we all know that an eye-catching, double-helical molecule of DNA carries instructions to manufacture and
assemble all the components of a living organism. The wealth of information encoded in DNA often overshadows its unusual physical properties, for example, the possibility of effective attraction between same-charge DNA molecules. Furthermore, the methods used to determine the informational content of DNA
—its nucleotide sequence—until now relied on biological processes.
In this talk, I will describe our recent efforts to characterize the physical properties of DNA through atomistic simulations and demonstrate how these properties can be exploited in a physics-based technology for sequencing DNA.
|Last modified:||22 October 2012 2.30 p.m.|