Lecture Anne-Sophie Duwez
|24 June 2011||FWN-Building 5113.0202, Nijenborgh 4, 9747 AG, Groningen|
|Speaker:||Prof. Dr. Anne-Sophie Duwez|
|Affiliation:||Dept. of Chemistry, University of Liège, Belgium|
|Title:||Probing single molecules with AFM: Force, dynamics and function|
|Date:||Fri Jun 24, 2011|
|Telephone:||+31 50 363 4736|
In 1952, Erwin Schrödinger wrote that we would never experiment with just one electron, one atom, or one molecule. Forty years later, methods derived from scanning probe microscopies allowed us to manipulate single atoms and molecules, and even single bonds. Single molecule force spectroscopy, which consists in trapping a molecule between an AFM tip and a surface, enables to probe (and/or to induce) molecular processes in situ and in real time through the application of mechanical forces. Such elegant experiments have provided unprecedented insights into the structure and function of many (biological) systems.
Here, we will discuss some of our recent results in the area of AFM-based single molecule force spectroscopy on bio-inspired systems, like DNA hybrid complexes, biohybrid copolymers of polypeptides, and molecular machines.
|Last modified:||22 October 2012 2.30 p.m.|