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Lecture Anne-Sophie Duwez


24 June 2011 FWN-Building 5113.0202, Nijenborgh 4, 9747 AG, Groningen
Speaker: Prof. Dr. Anne-Sophie Duwez
Affiliation: Dept. of Chemistry, University of Liège, Belgium
Title: Probing single molecules with AFM: Force, dynamics and function
Date: Fri Jun 24, 2011
Start: 14.00
Location: FWN-Building 5113.0202
Host: Petra Rudolf
Telephone: +31 50 363 4736


In 1952, Erwin Schrödinger wrote that we would never experiment with just one electron, one atom, or one molecule. Forty years later, methods derived from scanning probe microscopies allowed us to manipulate single atoms and molecules, and even single bonds. Single molecule force spectroscopy, which consists in trapping a molecule between an AFM tip and a surface, enables to probe (and/or to induce) molecular processes in situ and in real time through the application of mechanical forces. Such elegant experiments have provided unprecedented insights into the structure and function of many (biological) systems.




Here, we will discuss some of our recent results in the area of AFM-based single molecule force spectroscopy on bio-inspired systems, like DNA hybrid complexes, biohybrid copolymers of polypeptides, and molecular machines.




Last modified:22 October 2012 2.30 p.m.