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Zernike Institute for Advanced Materials Colloquium Itamar Willmer


01 December 2011 FWN-Building 5111.0080, Nijenborgh 4, 9747 AG, Groningen
Speaker: Prof. Dr. Itamar Willmer

Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel

Title: Biomolecular nanostructures for sensing, machinery and nanocircuitry
Date: Thu Dec 1, 2011
Start: 16.00 (Doors open and coffee available at 15.30)
Location: FWN-Building 5111.0080


The synthesis of biomolecule/nanoparticle hybrid systems or the self-assembly of biomolecular nano-structures provide materials of new emerging functionalities and properties.  The developments in the area of nanobiotechnology will be discussed by addressing the following topics: (i)  The electrical contacting of redox enzymes with electrodes by means of implanted metal nanoparticles, and the application of the systems for electrical biosensor, biofuel cells and new biocatalytic applications.  Also, the use of functionalized semiconductor quantum dots for biosensing using fluorescence resonance energy transfer, chemiluminescence resonance energy transfer and photoelectrochemical readout signals. (ii)  The use of the information encoded in nucleic acid structures to self-assemble into functional nanostructures.  This will be exemplified with self-organized DNA nanostructures acting as machines (tweezers, walkers, steppers and programmed catenane machineries), the self-assembly of nucleic acids into nanotubes of controlled diameters, the programmed positioning of proteins on DNA nanostructures for the activation of enzyme cascades, and the use of biomolecular templates for growing nanocircuitry.  (iii)  The tailoring of DNA replication/recycling machines for amplified sensing of DNA, and aptamer-substrate complexes.  The use of DNA molecular machines as potential alternatives for PCR will be discussed.

Last modified:22 October 2012 2.30 p.m.