Inclusion Complexes with Amylose
|G.Caroli at rug.nl|
Amylose is a natural polymer made up of α(1→4) bound glucose units. In its so called V form, amylose forms a helix which is hydrophilic on the outer part (due to the hydroxy groups) and hydrophobic in the inner part.
For this reason, V amylose can accomodate into its hydrophobic cavity organic molecules like fatty acids forming host/guest inclusion complexes. This is well known to occur in Nature, and happens also in our body. Hydrophobic polymeric guests can also be accomodated to form a polymer-polymer inclusion complex with amylose. However, not much has been reported in this respect.
In this research, we are investigating the mechanisms of formation of polytetrahydrofuran (PTHF)-amylose inclusion complexes. For example, PTHF and amylose can be covalently attached to form a block-copolymer, which is expected to give extra levels of hierarchy into the self-organization.
Moreover, the supramolecular ordering of the incusion complexes as well as their molecular recognition features can be exploited by employing the inclusion complexes as part of block copolymers. In this way, we expect to build self-assembled materials with new and complex architectures.
|Laatst gewijzigd:||01 juli 2015 10:53|