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OnderzoekVan Swinderen Institute

MSC Colloquium Dave Leigh

Roster

WhenWhere
06 October 2005 FWN-Building 5111.0080, Nijenborgh 4, 9747 AG, Groningen
Dave Leigh
Dave Leigh
Speaker: Dave Leigh
Affiliation: School of Chemistry, University of Edinburgh
Title: Tooling up for nanoworld: the magic of molecular machines
Date: Thu Oct 6, 2005
Start: 16.00 (Doors open and coffee available at 15.30)
Location: FWN-Building 5111.0080

Abstract

Mechanically-interlocked molecules (catenanes and rotaxanes) are increasingly attracting attention because their architectures offer properties and opportunities for exploitation not available to conventional materials.Metal-based systems and hydrogen bond-directed assembly offer powerful strategies for the synthesis of such structures on a scale where practical applications become realistic areas for study.

Here we discuss both simple and complex molecules-with-moving-parts; beginning with their synthesis and unusual properties and featuring their evolution into simple ‘molecular machines’. Remarkably, the movement of the components in such systems can be controlled by light, electrons, chemical reactions, pH, temperature or the nature of the environment.These techniques are now being applied to make molecular machines, nanoelectronics, switchable polymers, novel prodrugs and delivery systems, catalysts, reagents and ‘smart’ materials.1

1. For recent papers from our group see: Angew. Chem. Int. Ed. , 42, 5886-5589 (2003); Angew. Chem. Int. Ed. , 42, 3379-3383 (2003); Angew. Chem. Int. Ed ., 42, 2296-2300 (2003); J. Am. Chem. Soc. , 125, 13360-13361 (2003); J. Am. Chem. Soc., 125, 8644-8654 (2003); J. Am. Chem. Soc., 125, 2200-2207 (2003) ; Nature, 424, 174-179 (2003); Science , 299, 531 (2003); Proc. Natl. Acad. Sci. USA , 100, 10-14 (2003); Angew. Chem. Int. Ed. , 43, 1218-1221 (2004) ; Angew. Chem. Int. Ed. , 43, 1222-1224 (2004); Angew. Chem. Int. Ed., 43, 3260-3264 (2004); Angew. Chem. Int. Ed., 43, 3914-3918 (2004); Angew. Chem. Int. Ed., 44, 4557-4564 (2005); Angew. Chem. Int. Ed., 44, 3062-3067 (2005); J. Am. Chem. Soc. , 127 , 12612-12619 (2005).

 

 

 

Last modified:12 September 2014 11.22 a.m.