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OnderzoekVan Swinderen Institute

Prof. dr. M.L. Groot, Dept. of Biophysics, VU University Amsterdam: POR: A light-switched enzyme

Roster

WhenWhere
25 February 2010 FWN-Building 5111.0080, Nijenborgh 4, 9747 AG, Groningen
Speaker: Prof. dr. Marloes L. Groot
Affiliation: Dept. of Biophysics, VU University Amsterdam
Title:

POR: A light-switched enzyme

Date: 25-02-2010
Start: 16.00
Location: FWN-Building 5111.0080

Abstract

Proteins accelerate chemical reactions or even ensure that a substrate molecule undergoes a quite different reaction than in solution. To a large extent, these functions are determined by the structure of a specific protein. P roteins are however dynamic in structure, and conformational changes may modulate the activity of enzymes to the extent that they are switched on or off . In this colloquium I will present data collected on the enzyme POR, that demonstrate that it requires light to be activated, and light to perform catalysis. This makes POR a unique model system to control conformational changes and to study how they affect catalytic activity, including the initial ultrafast steps in catalysis. 

Last modified:12 September 2014 11.21 a.m.