Publication

Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session

Keijser, J. N., van Heuvelen, M. J. G., Nyakas, C., Tóth, K., Schoemaker, R. G., Zeinstra, E. & van der Zee, E. A., 2017, In : African journal of traditional, complementary, and alternative medicines : AJTCAM. 14, 4, p. 128-134 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Keijser, J. N., van Heuvelen, M. J. G., Nyakas, C., Tóth, K., Schoemaker, R. G., Zeinstra, E., & van der Zee, E. A. (2017). Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session. African journal of traditional, complementary, and alternative medicines : AJTCAM, 14(4), 128-134. https://doi.org/10.21010/ajtcam.v14i4.15

Author

Keijser, Jan N ; van Heuvelen, Marieke J G ; Nyakas, Csaba ; Tóth, Kata ; Schoemaker, Regien G ; Zeinstra, Edzard ; van der Zee, Eddy A. / Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session. In: African journal of traditional, complementary, and alternative medicines : AJTCAM. 2017 ; Vol. 14, No. 4. pp. 128-134.

Harvard

Keijser, JN, van Heuvelen, MJG, Nyakas, C, Tóth, K, Schoemaker, RG, Zeinstra, E & van der Zee, EA 2017, 'Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session', African journal of traditional, complementary, and alternative medicines : AJTCAM, vol. 14, no. 4, pp. 128-134. https://doi.org/10.21010/ajtcam.v14i4.15

Standard

Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session. / Keijser, Jan N; van Heuvelen, Marieke J G; Nyakas, Csaba; Tóth, Kata; Schoemaker, Regien G; Zeinstra, Edzard; van der Zee, Eddy A.

In: African journal of traditional, complementary, and alternative medicines : AJTCAM, Vol. 14, No. 4, 2017, p. 128-134.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Keijser JN, van Heuvelen MJG, Nyakas C, Tóth K, Schoemaker RG, Zeinstra E et al. Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2017;14(4):128-134. https://doi.org/10.21010/ajtcam.v14i4.15


BibTeX

@article{286998c58f30432ca24b6cb938030976,
title = "Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session",
abstract = "BACKGROUND: Whole body vibration (WBV) is a form of physical stimulation via mechanical vibrations transmitted to a subject. It is assumed that WBV induces sensory stimulation in cortical brain regions through the activation of skin and muscle receptors responding to the vibration. The effects of WBV on muscle strength are well described. However, little is known about the impact of WBV on the brain. Recently, it was shown in humans that WBV improves attention in an acute WBV protocol. Preclinical research is needed to unravel the underlying brain mechanism. As a first step, we examined whether chronic WBV improves attention in mice.MATERIAL AND METHODS: A custom made vibrating platform for mice with low intensity vibrations was used. Male CD1 mice (3 months of age) received five weeks WBV (30 Hz; 1.9 G), five days a week with sessions of five (n=12) or 30 (n=10) minutes. Control mice (pseudo-WBV; n=12 and 10 for the five and 30 minute sessions, respectively) were treated in a similar way, but did not receive the actual vibration. Object recognition tasks were used as an attention test (novel and spatial object recognition - the primary outcome measure). A Balance beam was used for motor performance, serving as a secondary outcome measure.RESULTS: WBV sessions of five (but not WBV sessions of 30 minutes) improved balance beam performance (mice gained 28{\%} in time needed to cross the beam) and novel object recognition (mice paid significantly more attention to the novel object) as compared to pseudo WBV, but no change was found for spatial object performance (mice did not notice the relocation). Although 30 minutes WBV sessions were not beneficial, it did not impair either attention or motor performance.CONCLUSION: These results show that brief sessions of WBV improve, next to motor performance, attention for object recognition, but not spatial cues of the objects. The selective improvement of attention in mice opens the avenue to unravel the underlying brain mechanisms.",
keywords = "Animals, Attention, Brain, Male, Mice, Motor Activity, Muscle Strength, Physical Therapy Modalities, Vibration, Journal Article",
author = "Keijser, {Jan N} and {van Heuvelen}, {Marieke J G} and Csaba Nyakas and Kata T{\'o}th and Schoemaker, {Regien G} and Edzard Zeinstra and {van der Zee}, {Eddy A}",
year = "2017",
doi = "10.21010/ajtcam.v14i4.15",
language = "English",
volume = "14",
pages = "128--134",
journal = "African journal of traditional, complementary, and alternative medicines : AJTCAM",
issn = "2505-0044",
number = "4",

}

RIS

TY - JOUR

T1 - Whole body vibration improves attention and motor performance in mice depending on the duration of the whole-body vibration session

AU - Keijser, Jan N

AU - van Heuvelen, Marieke J G

AU - Nyakas, Csaba

AU - Tóth, Kata

AU - Schoemaker, Regien G

AU - Zeinstra, Edzard

AU - van der Zee, Eddy A

PY - 2017

Y1 - 2017

N2 - BACKGROUND: Whole body vibration (WBV) is a form of physical stimulation via mechanical vibrations transmitted to a subject. It is assumed that WBV induces sensory stimulation in cortical brain regions through the activation of skin and muscle receptors responding to the vibration. The effects of WBV on muscle strength are well described. However, little is known about the impact of WBV on the brain. Recently, it was shown in humans that WBV improves attention in an acute WBV protocol. Preclinical research is needed to unravel the underlying brain mechanism. As a first step, we examined whether chronic WBV improves attention in mice.MATERIAL AND METHODS: A custom made vibrating platform for mice with low intensity vibrations was used. Male CD1 mice (3 months of age) received five weeks WBV (30 Hz; 1.9 G), five days a week with sessions of five (n=12) or 30 (n=10) minutes. Control mice (pseudo-WBV; n=12 and 10 for the five and 30 minute sessions, respectively) were treated in a similar way, but did not receive the actual vibration. Object recognition tasks were used as an attention test (novel and spatial object recognition - the primary outcome measure). A Balance beam was used for motor performance, serving as a secondary outcome measure.RESULTS: WBV sessions of five (but not WBV sessions of 30 minutes) improved balance beam performance (mice gained 28% in time needed to cross the beam) and novel object recognition (mice paid significantly more attention to the novel object) as compared to pseudo WBV, but no change was found for spatial object performance (mice did not notice the relocation). Although 30 minutes WBV sessions were not beneficial, it did not impair either attention or motor performance.CONCLUSION: These results show that brief sessions of WBV improve, next to motor performance, attention for object recognition, but not spatial cues of the objects. The selective improvement of attention in mice opens the avenue to unravel the underlying brain mechanisms.

AB - BACKGROUND: Whole body vibration (WBV) is a form of physical stimulation via mechanical vibrations transmitted to a subject. It is assumed that WBV induces sensory stimulation in cortical brain regions through the activation of skin and muscle receptors responding to the vibration. The effects of WBV on muscle strength are well described. However, little is known about the impact of WBV on the brain. Recently, it was shown in humans that WBV improves attention in an acute WBV protocol. Preclinical research is needed to unravel the underlying brain mechanism. As a first step, we examined whether chronic WBV improves attention in mice.MATERIAL AND METHODS: A custom made vibrating platform for mice with low intensity vibrations was used. Male CD1 mice (3 months of age) received five weeks WBV (30 Hz; 1.9 G), five days a week with sessions of five (n=12) or 30 (n=10) minutes. Control mice (pseudo-WBV; n=12 and 10 for the five and 30 minute sessions, respectively) were treated in a similar way, but did not receive the actual vibration. Object recognition tasks were used as an attention test (novel and spatial object recognition - the primary outcome measure). A Balance beam was used for motor performance, serving as a secondary outcome measure.RESULTS: WBV sessions of five (but not WBV sessions of 30 minutes) improved balance beam performance (mice gained 28% in time needed to cross the beam) and novel object recognition (mice paid significantly more attention to the novel object) as compared to pseudo WBV, but no change was found for spatial object performance (mice did not notice the relocation). Although 30 minutes WBV sessions were not beneficial, it did not impair either attention or motor performance.CONCLUSION: These results show that brief sessions of WBV improve, next to motor performance, attention for object recognition, but not spatial cues of the objects. The selective improvement of attention in mice opens the avenue to unravel the underlying brain mechanisms.

KW - Animals

KW - Attention

KW - Brain

KW - Male

KW - Mice

KW - Motor Activity

KW - Muscle Strength

KW - Physical Therapy Modalities

KW - Vibration

KW - Journal Article

U2 - 10.21010/ajtcam.v14i4.15

DO - 10.21010/ajtcam.v14i4.15

M3 - Article

VL - 14

SP - 128

EP - 134

JO - African journal of traditional, complementary, and alternative medicines : AJTCAM

JF - African journal of traditional, complementary, and alternative medicines : AJTCAM

SN - 2505-0044

IS - 4

ER -

ID: 50392050