Publication

VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis

Yeshaw, W. M., 2018, [Groningen]: University of Groningen. 136 p.

Research output: ThesisThesis fully internal (DIV)Academic

APA

Yeshaw, W. M. (2018). VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis. [Groningen]: University of Groningen.

Author

Yeshaw, Wondwossen Melaku. / VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis. [Groningen] : University of Groningen, 2018. 136 p.

Harvard

Yeshaw, WM 2018, 'VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis', Doctor of Philosophy, University of Groningen, [Groningen].

Standard

VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis. / Yeshaw, Wondwossen Melaku.

[Groningen] : University of Groningen, 2018. 136 p.

Research output: ThesisThesis fully internal (DIV)Academic

Vancouver

Yeshaw WM. VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis. [Groningen]: University of Groningen, 2018. 136 p.


BibTeX

@phdthesis{75719cd9442a405b82a934d629e260ea,
title = "VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis",
abstract = "Over 30 years ago, yeast vacuolar protein sorting 13 (Vps13) was discovered as one of the proteins required for carboxypeptidase Y sorting. The presence of four human Vps13 orthologues and their associations with the onsets of clinically distinct neurological and developmental disorders calls for the demand to mechanistically study each VPS13 protein in multicellular organisms. The challenge has been in defining the localization and functional contributions of each VPS13 family member in molecular pathways. Data presented in this thesis attempts to uncover the subcellular localization and molecular functions of VPS13A in healthy tissue and the consequences of its absence in a Drosophila and human cell ChAc models.",
author = "Yeshaw, {Wondwossen Melaku}",
year = "2018",
language = "English",
isbn = "978-94-034-0767-8",
publisher = "University of Groningen",
school = "University of Groningen",

}

RIS

TY - THES

T1 - VPS13A is a multitasking protein at the crossroads between organelle communication and protein homeostasis

AU - Yeshaw, Wondwossen Melaku

PY - 2018

Y1 - 2018

N2 - Over 30 years ago, yeast vacuolar protein sorting 13 (Vps13) was discovered as one of the proteins required for carboxypeptidase Y sorting. The presence of four human Vps13 orthologues and their associations with the onsets of clinically distinct neurological and developmental disorders calls for the demand to mechanistically study each VPS13 protein in multicellular organisms. The challenge has been in defining the localization and functional contributions of each VPS13 family member in molecular pathways. Data presented in this thesis attempts to uncover the subcellular localization and molecular functions of VPS13A in healthy tissue and the consequences of its absence in a Drosophila and human cell ChAc models.

AB - Over 30 years ago, yeast vacuolar protein sorting 13 (Vps13) was discovered as one of the proteins required for carboxypeptidase Y sorting. The presence of four human Vps13 orthologues and their associations with the onsets of clinically distinct neurological and developmental disorders calls for the demand to mechanistically study each VPS13 protein in multicellular organisms. The challenge has been in defining the localization and functional contributions of each VPS13 family member in molecular pathways. Data presented in this thesis attempts to uncover the subcellular localization and molecular functions of VPS13A in healthy tissue and the consequences of its absence in a Drosophila and human cell ChAc models.

M3 - Thesis fully internal (DIV)

SN - 978-94-034-0767-8

PB - University of Groningen

CY - [Groningen]

ER -

ID: 61750966