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Volume-controlled versus short drainage after inguinofemoral lymphadenectomy in vulvar cancer patients: A Dutch nationwide prospective study

Pouwer, A. W., Hinten, F., van der Velden, J., Smolders, R. G. V., Slangen, B. F. M., Zijlmans, H. J. M. A. A., IntHout, J., van der Zee, A. G. J., Boll, D., Gaarenstroom, K. N., Arts, H. J. & de Hullu, J. A., Sep-2017, In : Gynecologic Oncology. 146, 3, p. 580-587 8 p.

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  • Volume-controlled versus short drainage after inguinofemoral lymphadenectomy in vulvar cancer patients

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DOI

  • A. W. Pouwer
  • F. Hinten
  • J. van der Velden
  • R. G. V. Smolders
  • B. F. M. Slangen
  • H. J. M. A. A. Zijlmans
  • J. IntHout
  • A. G. J. van der Zee
  • D. Boll
  • K. N. Gaarenstroom
  • H. J. Arts
  • J. A. de Hullu

Objective. Inguinofemoral lymphadenectomy for patients with vulvar squamous cell carcinoma is associated with a high incidence of postoperative wound complications, which may be influenced by inguinal drain management. The aim of this nationwide prospective study (MAMBO: Morbidity And Measurement of the BOdy) was to assess the feasibility and the incidence of complications after volume-controlled versus short drainage.

Methods. The MAMBO study consisted of two observational studies in all eight oncology centers in the Netherlands, conducted between 2012 and 2016. In the first study, the drain was removed when the production was

Results. We included 77 patients (139 groins) for volume-controlled drainage and 64 patients (112 groins) for short drainage. Volume-controlled drainage was associated with significant less lymphocele formation. Moreover, we found no difference in wound infection or primary wound breakdown. The estimated incidence of one or more complications was 46% per groin after volume-controlled drainage versus 75% after short drainage, (RD 29% (95% CI 8, 49) p = 0.006).

Conclusions. This prospective study shows that volume-controlled drainage is associated with significantly less complications compared to short drainage. We therefore recommend volume-controlled drainage after inguinofemoral lymphadenectomy in patients with vulvar squamous cell carcinoma.

Original languageEnglish
Pages (from-to)580-587
Number of pages8
JournalGynecologic Oncology
Volume146
Issue number3
Publication statusPublished - Sep-2017

    Keywords

  • Vulvar cancer, Vulvar squamous cell carcinoma, Inguinofemoral lymphadenectomy, Drain management, Postoperative complications, Morbidity, LYMPH-NODE DISSECTION, PROSPECTIVE RANDOMIZED-TRIAL, LOWER-LIMB LYMPHEDEMA, LOW VACUUM DRAINAGE, BREAST-CANCER, AXILLARY LYMPHADENECTOMY, INGUINAL LYMPHADENECTOMY, RADICAL-MASTECTOMY, SAPHENOUS-VEIN, MORBIDITY

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