Publication

Viruses, Artificial Viruses and Virus-Based Structures for Biomedical Applications

van Rijn, P. & Schirhagl, R., 22-Jun-2016, In : Advanced healthcare materials. 5, 12, p. 1386-1400 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Nanobiomaterials such as virus particles and artificial virus particles offer tremendous opportunities to develop new biomedical applications such as drug- or gene-delivery, imaging and sensing but also improve understanding of biological mechanisms. Recent advances within the field of virus-based systems give insights in how to mimic viral structures and virus assembly processes as well as understanding biodistribution, cell/tissue targeting, controlled and triggered disassembly or release and circulation times. All these factors are of high importance for virus-based functional systems. This review illustrates advances in mimicking and enhancing or controlling these aspects to a high degree toward delivery and imaging applications.

Original languageEnglish
Pages (from-to)1386-1400
Number of pages15
JournalAdvanced healthcare materials
Volume5
Issue number12
Publication statusPublished - 22-Jun-2016

    Keywords

  • biomedical applications, delivery, imaging, nanobiomaterials, virus particles, TOBACCO-MOSAIC-VIRUS, MRI CONTRAST AGENTS, MULTIFUNCTIONAL VIRAL NANOPARTICLES, QUARTZ-CRYSTAL MICROBALANCE, GREEN FLUORESCENT PROTEIN, TUMOR-BEARING MICE, IN-VIVO, DRUG-DELIVERY, GENE DELIVERY, POLY(ETHYLENE GLYCOL)

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