Vaccinatieprogramma’s in NederlandTulen, A. D., van Wijhe, M., Korthals Altes, H., McDonald, S. A., de Melker, H. E., Postma, M. J. & Wallinga, J., 20-Sep-2018, In : Nederlands Tijdschrift voor Geneeskunde. 162
Research output: Contribution to journal › Article › Academic › peer-review
OBJECTIVE: To quantify the impact of long-standing vaccination programmes on notified cases in the Netherlands.
DESIGN: Estimates based on model projections of historical morbidity data.
METHOD: We collected and digitised previously unavailable monthly case notifications of diphtheria, poliomyelitis, mumps and rubella in the Netherlands over the period 1919-2015. Poisson regression models accounting for seasonality, multi-year cycles, secular trends and auto-correlation were fit to pre-vaccination periods. Cases averted were calculated as the difference between observed and expected cases based on model projections.
RESULTS: In the first 13 years of mass vaccinations, case notifications declined rapidly with 18,900 (95%-CI: 12,000-28,600) notified cases of diphtheria averted, 5100 (95%-CI: 2200-13,500) cases of poliomyelitis, and 1800 (95%-CI: 1000-3200) cases of mumps. Vaccination of 11-year-old girls against rubella averted 13700 (95%-CI: 1400-38,300) cases, while universal rubella vaccination averted 700 (95%-CI: 80-2300) cases.
CONCLUSION: These findings show that vaccination programmes have contributed substantially to the reduction of infectious diseases in the Netherlands.
|Translated title of the contribution||Quantifying the impact of mass vaccination programmes on notified cases in the Netherlands|
|Journal||Nederlands Tijdschrift voor Geneeskunde|
|Publication status||Published - 20-Sep-2018|