Tritylamine as an Ammonia Surrogate in the Ugi Tetrazole SynthesisZhao, T., Boltjes, A., Herdtweck, E. & Doemling, A., 1-Feb-2013, In : Organic letters. 15, 3, p. 639-641 3 p.
Research output: Contribution to journal › Article › Academic › peer-review
The role of tritylamine is introduced as a convenient ammonia substitute in the Ugi tetrazole synthesis. Fifteen examples and their mild cleavage products are described In satisfactory to good yields. N-Unsubstituted alpha-aminotetrazoles are important compounds with annotated biological activities, and the described two-step synthesis provided an alternative route to otherwise difficult to access derivatives.
|Number of pages||3|
|Publication status||Published - 1-Feb-2013|
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