Publication

Transmission of periodontal bacteria and models of infection

van Winkelhoff, AJ. & Boutaga, K., Oct-2005, In : Journal of Clinical Periodontology. 32, p. 16-27 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

  • AJ van Winkelhoff
  • K Boutaga

Background: Bacteria play an essential role in the aetiology of periodontitis. Most bacterial species isolated from subgingival plaque are indigenous to the oral cavity. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis are detected infrequently in periodontal health, which makes these species prime candidates to study person-to-person transmission. The aim of the present study was to review the literature on transmission of these periodontal bacterial species.

Method: We review the literature on bacterial typing techniques and summarize the information on clonal distribution of A. actinomycetemcomitans and P. gingivalis in family units based on different typing techniques in order to establish the likelihood for person-to-person transmission of these periodontal pathogens.

Results: Vertical transmission of A. actinomycetemcomitans is estimated to be between 30% and 60%, whereas vertical transmission of P. gingivalis has rarely been observed. Horizontal transmission between spouses ranges between 14% and 60% for A. actinomycetemcomitans and between 30% and 75% for P. gingivalis. There is some evidence to show that cohabitation with a periodontitis patient influences the periodontal status of the spouse; however, substantially more information is needed to prove this hypothesis.

Conclusions: Transmission of putative periodontal pathogens between family members has been shown. The clinical consequences of these events have been poorly documented. Based on the current knowledge, screening for and prevention of transmission of specific virulent clones of A. actinomycetemcomitans may be feasible and effective in preventing some forms of periodontal disease. P. gingivalis is usually recovered from diseased adult subjects, and transmission of this pathogens seems largely restricted to adult individuals. Horizontal transmissiom of P. gingivalis may therefore be controlled by periodontal treatment involving elimination or significant suppression of the pathogen in diseased individuals and by a high standard of oral hygiene.

Original languageEnglish
Pages (from-to)16-27
Number of pages12
JournalJournal of Clinical Periodontology
Volume32
Publication statusPublished - Oct-2005
Externally publishedYes
Event5th European Workshop on Periodontology - Etiology and Pathogensis Leading to Preventive Concepts - Ittingen, Switzerland
Duration: 5-Feb-20059-Feb-2005

Event

5th European Workshop on Periodontology - Etiology and Pathogensis Leading to Preventive Concepts

05/02/200509/02/2005

Switzerland

Event: Conference

    Keywords

  • bacteria, transmission, periodontitis, infection, bacterial typing, LOCALIZED JUVENILE PERIODONTITIS, SUBGINGIVAL PLAQUE SAMPLES, POLYMERASE-CHAIN-REACTION, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PORPHYROMONAS-GINGIVALIS, BACTEROIDES-INTERMEDIUS, A-ACTINOMYCETEMCOMITANS, ADULT PERIODONTITIS, CAPSULAR SEROTYPES, VIRULENCE FACTORS

ID: 13927251