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Translational gap in pediatric septic shock management: an ESPNIC perspective

ESPNIC Refractory Septic Shock Def, Infect Systemic Inflammation Sepsi, Morin, L., Kneyber, M., Jansen, N. J. G., Peters, M. J., Javouhey, E., Nadel, S., Maclaren, G., Schlapbach, L. J. & Tissieres, P., 28-Jun-2019, In : Annals of Intensive Care. 9, 6 p., 73.

Research output: Contribution to journalArticleAcademicpeer-review

  • ESPNIC Refractory Septic Shock Def
  • Infect Systemic Inflammation Sepsi
  • Luc Morin
  • Martin Kneyber
  • Nicolaas J. G. Jansen
  • Mark J. Peters
  • Etienne Javouhey
  • Simon Nadel
  • Graeme Maclaren
  • Luregn Jan Schlapbach
  • Pierre Tissieres

BackgroundThe Surviving Sepsis Campaign and the American College of Critical Care Medicine guidelines have provided recommendations for the management of pediatric septic shock patients. We conducted a survey among the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) members to assess variations to these recommendations.MethodsA total of 114 pediatric intensive care physicians completed an electronic survey. The survey consisted of four standardized clinical cases exploring seven clinical scenarios.ResultsAmong the seven different clinical scenarios, the types of fluids were preferentially non-synthetic colloids (albumin) and crystalloids (isotonic saline) and volume expansion was not limited to 60ml/kg. Early intubation for mechanical ventilation was used by 70% of the participants. Norepinephrine was stated to be used in 94% of the PICU physicians surveyed, although dopamine or epinephrine is recommended as first-line vasopressors in pediatric septic shock. When norepinephrine was used, the addition of another inotrope was frequent. Specific drugs such as vasopressin or enoximone were used in

Original languageEnglish
Article number73
Number of pages6
JournalAnnals of Intensive Care
Volume9
Publication statusPublished - 28-Jun-2019

    Keywords

  • CLINICAL-PRACTICE PARAMETERS, RANDOMIZED CONTROLLED-TRIAL, CRITICALLY-ILL CHILDREN, HEMODYNAMIC SUPPORT, AMERICAN-COLLEGE, FLUID BALANCE, SEVERE SEPSIS, CARE, MULTICENTER, EPINEPHRINE

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