Thrombolysis for Acute Ischemic StrokeUyttenboogaart, M., De Keyser, J. & Luijckx, G. J., Oct-2009, In : Current topics in medicinal chemistry. 9, 14, p. 1285-1290 6 p.
Research output: Contribution to journal › Review article › Academic › peer-review
In the last decennium, thrombolytic therapy has changed the management of acute ischemic stroke. Randomized clinical studies have demonstrated that intravenous thrombolysis with tissue plasminogen activator improves functional outcomes. Recently the time window for intravenous thrombolysis has been extended from 3 to 4.5 hours after stroke onset, which will allow more stroke patients to benefit from this treatment. Currently several studies are investigating how to improve recanalization rates of thrombolytic therapy. In this review several aspects of intravenous and intra-arterial thrombolysis are discussed.
|Number of pages||6|
|Journal||Current topics in medicinal chemistry|
|Publication status||Published - Oct-2009|
- TISSUE-PLASMINOGEN ACTIVATOR, RANDOMIZED CONTROLLED-TRIAL, CEREBRAL-ARTERY STROKE, INTRAVENOUS THROMBOLYSIS, TIME WINDOW, INTERVENTIONAL MANAGEMENT, INTRACEREBRAL HEMORRHAGE, TPA THERAPY, 3 H, ALTEPLASE