Publication

Things we know and do not know about motoneurones

Kernell, D., 2002, SENSORIMOTOR CONTROL OF MOVEMENT AND POSTURE. Gandevia, SC., Proske, U. & Stuart, DG. (eds.). NEW YORK: Kluwer Academic/Plenum Publishers, p. 187-192 6 p. (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY; vol. 508).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

  • D Kernell

An introductory survey is given of the cellular physiology of motoneurones (MNs). Steady driving currents, applied to individual cells through microelectrodes, may be used for determining such key parameters as the range of possible discharge rates and the shape and steepness of the curve relating discharge frequency to current intensity (f-I relation). Quantitatively, MN properties may vary considerably between animal species and between cells innervating different types of muscle fibres. Central synapses impinging upon MNs often simply provide "driving" currents, altering MN discharge rate largely in accordance with the f-I relation. In addition, metabotropic synapses may have "MN-modifying" effects, altering MN membrane and activation properties in various ways. Studies of MN firing and response patterns in normal and pathological motor behaviour is essential for evaluating the functional role of short- and long-term modifications of MN properties.

Original languageEnglish
Title of host publicationSENSORIMOTOR CONTROL OF MOVEMENT AND POSTURE
EditorsSC Gandevia, U Proske, DG Stuart
Place of PublicationNEW YORK
PublisherKluwer Academic/Plenum Publishers
Pages187-192
Number of pages6
ISBN (Print)0-306-47285-6
Publication statusPublished - 2002
EventConference on Neural Mechanisms of Sensorimotor Control - , Australia
Duration: 3-Sep-20016-Sep-2001

Publication series

NameADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
PublisherKLUWER ACADEMIC/PLENUM PUBL
Volume508
ISSN (Print)0065-2598

Other

OtherConference on Neural Mechanisms of Sensorimotor Control
CountryAustralia
Period03/09/200106/09/2001

Event

Conference on Neural Mechanisms of Sensorimotor Control

03/09/200106/09/2001

Australia

Event: Other

    Keywords

  • CAT SPINAL MOTONEURONS, PERSISTENT INWARD CURRENT, FIRING RATE MODULATION, PLATEAU POTENTIALS, SYNAPTIC ACTIVATION, ALPHA-MOTONEURONES, TIME-COURSE, IN-VIVO, BISTABILITY, MUSCLE

ID: 4037663