Publication

Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster

Soto-Padilla, A., Ruijsink, R., Sibon, O. C. M., van Rijn, H. & Billeter, J-C., 22-May-2018, In : Journal of Experimental Biology. 221, 10, 9 p., 74151.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Soto-Padilla, A., Ruijsink, R., Sibon, O. C. M., van Rijn, H., & Billeter, J-C. (2018). Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster. Journal of Experimental Biology, 221(10), [74151]. https://doi.org/10.1242/jeb.174151

Author

Soto-Padilla, Andrea ; Ruijsink, Rick ; Sibon, Ody C M ; van Rijn, Hedderik ; Billeter, Jean-Christophe. / Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster. In: Journal of Experimental Biology. 2018 ; Vol. 221, No. 10.

Harvard

Soto-Padilla, A, Ruijsink, R, Sibon, OCM, van Rijn, H & Billeter, J-C 2018, 'Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster', Journal of Experimental Biology, vol. 221, no. 10, 74151. https://doi.org/10.1242/jeb.174151

Standard

Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster. / Soto-Padilla, Andrea; Ruijsink, Rick; Sibon, Ody C M; van Rijn, Hedderik; Billeter, Jean-Christophe.

In: Journal of Experimental Biology, Vol. 221, No. 10, 74151, 22.05.2018.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Soto-Padilla A, Ruijsink R, Sibon OCM, van Rijn H, Billeter J-C. Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster. Journal of Experimental Biology. 2018 May 22;221(10). 74151. https://doi.org/10.1242/jeb.174151


BibTeX

@article{6d35e75cd0cf4bec871ee7a6d2c1185d,
title = "Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster",
abstract = "Temperature influences physiology and behavior of all organisms. For ectotherms, which lack central temperature regulation, temperature adaptation requires sheltering from or moving to a heat source. As temperature constrains the rate of metabolic reactions, it can directly affect ectotherm physiology and thus behavioral performance. This direct effect is particularly relevant for insects whose small body readily equilibrates with ambient temperature. In fact, models of enzyme kinetics applied to insect behavior predict performance at different temperatures, suggesting that thermal physiology governs behavior. However, insects also possess thermosensory neurons critical for locating preferred temperatures, showing cognitive control. This suggests that temperature-related behavior can emerge directly from a physiological effect, indirectly as consequence of thermosensory processing, or through both. To separate the roles of thermal physiology and cognitive control, we developed an arena that allows fast temperature changes in time and space, and in which animals' movements are automatically quantified. We exposed wild-type and thermosensory receptor mutants Drosophila melanogaster to a dynamic temperature environment and tracked their movements. The locomotor speed of wild-type flies closely matched models of enzyme kinetics, but the behavior of thermosensory mutants did not. Mutations in thermosensory receptor dTrpA1 (Transient receptor potential) expressed in the brain resulted in a complete lack of response to temperature changes, while mutation in peripheral thermosensory receptor Gr28b(D) resulted in diminished response. We conclude that flies react to temperature through cognitive control, informed by interactions between various thermosensory neurons, whose behavioral output resembles that of enzyme kinetics.",
keywords = "Journal Article",
author = "Andrea Soto-Padilla and Rick Ruijsink and Sibon, {Ody C M} and {van Rijn}, Hedderik and Jean-Christophe Billeter",
note = "{\circledC} 2018. Published by The Company of Biologists Ltd.",
year = "2018",
month = "5",
day = "22",
doi = "10.1242/jeb.174151",
language = "English",
volume = "221",
journal = "Journal of Experimental Biology",
issn = "0022-0949",
publisher = "COMPANY OF BIOLOGISTS LTD",
number = "10",

}

RIS

TY - JOUR

T1 - Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster

AU - Soto-Padilla, Andrea

AU - Ruijsink, Rick

AU - Sibon, Ody C M

AU - van Rijn, Hedderik

AU - Billeter, Jean-Christophe

N1 - © 2018. Published by The Company of Biologists Ltd.

PY - 2018/5/22

Y1 - 2018/5/22

N2 - Temperature influences physiology and behavior of all organisms. For ectotherms, which lack central temperature regulation, temperature adaptation requires sheltering from or moving to a heat source. As temperature constrains the rate of metabolic reactions, it can directly affect ectotherm physiology and thus behavioral performance. This direct effect is particularly relevant for insects whose small body readily equilibrates with ambient temperature. In fact, models of enzyme kinetics applied to insect behavior predict performance at different temperatures, suggesting that thermal physiology governs behavior. However, insects also possess thermosensory neurons critical for locating preferred temperatures, showing cognitive control. This suggests that temperature-related behavior can emerge directly from a physiological effect, indirectly as consequence of thermosensory processing, or through both. To separate the roles of thermal physiology and cognitive control, we developed an arena that allows fast temperature changes in time and space, and in which animals' movements are automatically quantified. We exposed wild-type and thermosensory receptor mutants Drosophila melanogaster to a dynamic temperature environment and tracked their movements. The locomotor speed of wild-type flies closely matched models of enzyme kinetics, but the behavior of thermosensory mutants did not. Mutations in thermosensory receptor dTrpA1 (Transient receptor potential) expressed in the brain resulted in a complete lack of response to temperature changes, while mutation in peripheral thermosensory receptor Gr28b(D) resulted in diminished response. We conclude that flies react to temperature through cognitive control, informed by interactions between various thermosensory neurons, whose behavioral output resembles that of enzyme kinetics.

AB - Temperature influences physiology and behavior of all organisms. For ectotherms, which lack central temperature regulation, temperature adaptation requires sheltering from or moving to a heat source. As temperature constrains the rate of metabolic reactions, it can directly affect ectotherm physiology and thus behavioral performance. This direct effect is particularly relevant for insects whose small body readily equilibrates with ambient temperature. In fact, models of enzyme kinetics applied to insect behavior predict performance at different temperatures, suggesting that thermal physiology governs behavior. However, insects also possess thermosensory neurons critical for locating preferred temperatures, showing cognitive control. This suggests that temperature-related behavior can emerge directly from a physiological effect, indirectly as consequence of thermosensory processing, or through both. To separate the roles of thermal physiology and cognitive control, we developed an arena that allows fast temperature changes in time and space, and in which animals' movements are automatically quantified. We exposed wild-type and thermosensory receptor mutants Drosophila melanogaster to a dynamic temperature environment and tracked their movements. The locomotor speed of wild-type flies closely matched models of enzyme kinetics, but the behavior of thermosensory mutants did not. Mutations in thermosensory receptor dTrpA1 (Transient receptor potential) expressed in the brain resulted in a complete lack of response to temperature changes, while mutation in peripheral thermosensory receptor Gr28b(D) resulted in diminished response. We conclude that flies react to temperature through cognitive control, informed by interactions between various thermosensory neurons, whose behavioral output resembles that of enzyme kinetics.

KW - Journal Article

U2 - 10.1242/jeb.174151

DO - 10.1242/jeb.174151

M3 - Article

VL - 221

JO - Journal of Experimental Biology

JF - Journal of Experimental Biology

SN - 0022-0949

IS - 10

M1 - 74151

ER -

ID: 56967183