The YidC/Oxa1/Alb3 protein family: common principles and distinct featuresSaller, M. J., Wu, Z. C., de Keyzer, J. & Driessen, A. J. M., Nov-2012, In : Biological Chemistry. 393, 11, p. 1279-1290 12 p.
Research output: Contribution to journal › Review article › Academic › peer-review
The members of the YidC/Oxa1/Alb3 protein family are evolutionary conserved in all three domains of life. They facilitate the insertion of membrane proteins into bacterial, mitochondrial, and thylakoid membranes and have been implicated in membrane protein folding and complex formation. The major classes of substrates are small hydrophobic subunits of large energy-transducing complexes involved in respiration and light capturing. All YidC-like proteins share a conserved membrane region, whereas the N- and C-terminal regions are diverse and fulfill accessory functions in protein targeting.
|Number of pages||12|
|Publication status||Published - Nov-2012|
- bacteria, biogenesis, membrane protein insertion, mitochondria, targeting, thylakoids, SIGNAL RECOGNITION PARTICLE, ESCHERICHIA-COLI YIDC, PF3 COAT PROTEIN, INNER MEMBRANE-PROTEINS, INDEPENDENT GENE DUPLICATIONS, SACCHAROMYCES-CEREVISIAE, CYTOCHROME-OXIDASE, PERIPLASMIC DOMAIN, BACILLUS-SUBTILIS, SUBUNIT-C