The vascular nature of COVID-19Oudkerk, M., Kuijpers, D., Oudkerk, S. F. & van Beek, E. J., 2020, In : British journal of radiology. 93, 1113, p. 20200718 3 p., 20200718.
Research output: Contribution to journal › Editorial › Academic › peer-review
A potential link between mortality, D-dimer values and a prothrombotic syndrome has been reported in COVID-19 patients. The National Institute for Public Health of the Netherlands published a report for guidance on diagnosis, prevention and treatment of thromboembolic complications in COVID-19 with a new vascular disease concept. The analysis of all available current medical, laboratory and imaging data on COVID-19 confirms that symptoms and diagnostic tests can not be explained by impaired pulmonary ventilation. Further imaging and pathological investigations confirm that the COVID-19 syndrome is explained by perfusion disturbances first in the lung, but consecutively in all organs of the body. Damage of the microvasculature by SARS 1 and SARS 2 (COVID-19) viruses causes microthrombotic changes in the pulmonary capillaries and organs leading to macrothrombosis and emboli. Therefore anticoagulant profylaxis, close lab and CT imaging monitoring and early anticoagulant therapy are indicated.
|Number of pages||3|
|Journal||British journal of radiology|
|Early online date||31-Jul-2020|
|Publication status||Published - 2020|