The role of pilocarpine in the reduction of radiation induced damage to the salivary glandsBurlage, F. R., 2008, [S.n.]. 135 p.
Research output: Thesis › Thesis fully internal (DIV)
Regarding late morbidity, hyposalivation is one of the most frequently reported radiation-induced side effects which has a negative impact on health-related quality of life [1;2]. Besides the subjective sensation of a dry mouth (xerostomia), saliva also plays a major role in speech, taste perception, mastication, bolus formation, swallowing, rinsing the mouth, clearing and diluting food detritus and bacterial matter, and mucosal protection [3;4]. In this thesis we investigated the role and the mechanisms of pilocarpine treatment during radiotherapy in the prevention and reduction of radiation-induced hyposalivation.
|Qualification||Doctor of Philosophy|
|Publication status||Published - 2008|
- Proefschriften (vorm), Pilocarpine , Stralingsbeschadiging, Speekselklieren , Bestr, Xerostomie , Tumoren, Speeksel, neoplasmata, gezwellen, radiologie
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