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The role of N-terminal pro-B-type natriuretic peptide in prognostic evaluation of heart failure

Lam, C. S. P., Li, Y-H., Bayes-Genis, A., Ariyachaipanich, A., Do Quang Huan, Sato, N., Kahale, P., Ta Manh Cuong, Dong, Y., Li, X. & Zhou, Y., Jun-2019, In : Journal of the chinese medical association. 82, 6, p. 447-451 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

  • Carolyn S. P. Lam
  • Yi-Heng Li
  • Antoni Bayes-Genis
  • Aekarach Ariyachaipanich
  • Do Quang Huan
  • Naoki Sato
  • Pravin Kahale
  • Ta Manh Cuong
  • Yugang Dong
  • Xinli Li
  • Yanli Zhou

Heart failure (HF) is a growing challenge in the Asia Pacific region. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-established tool for diagnosis of HF; however, it is relatively underutilized in predicting adverse outcomes in HF. Multiple studies have demonstrated the prognostic role of NT-proBNP in HF. A single value of NT-proBNP >5000 pg/mL predicts a worse outcome in hospitalized patients with HF with reduced ejection fraction (HFrEF). In stable outpatients with HFrEF, NT-proBNP > 1000 pg/mL predicts a poorer prognosis. NT-proBNP provides the same prognostic information in patients with HF with preserved ejection fraction (HFpEF) as in those with HFrEF. An expert panel composed of cardiologists mainly from Asia Pacific region was convened to discuss the utility of NT-proBNP in HF prognostication. This article summarizes available scientific evidence and consensus recommendations from the meeting.

Original languageEnglish
Pages (from-to)447-451
Number of pages5
JournalJournal of the chinese medical association
Volume82
Issue number6
Publication statusPublished - Jun-2019

    Keywords

  • Heart failure, Natriuretic peptide, Prognosis, EJECTION FRACTION, DIAGNOSIS, THERAPY, RISK, ASIA, HOSPITALIZATION, MORTALITY, COMBINATION, PERFORMANCE, POPULATION

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