Publication

The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia

Piersma, D., Fuermaier, A. B. M., de Waard, D., De Deyn, P. P., Davidse, R. J., de Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Vermeeren, A., Ponds, R., Verhey, F., Brouwer, W. H. & Tucha, O., Dec-2018, In : Acta neurologica belgica. 118, 4, p. 637–642 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Piersma, D., Fuermaier, A. B. M., de Waard, D., De Deyn, P. P., Davidse, R. J., de Groot, J., ... Tucha, O. (2018). The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia. Acta neurologica belgica, 118(4), 637–642. https://doi.org/10.1007/s13760-018-1036-3

Author

Piersma, D. ; Fuermaier, A. B. M. ; de Waard, D. ; De Deyn, P. P. ; Davidse, R. J. ; de Groot, J. ; Doumen, M. J. A. ; Bredewoud, R. A. ; Claesen, R. ; Lemstra, A. W. ; Vermeeren, A. ; Ponds, R. ; Verhey, F. ; Brouwer, W. H. ; Tucha, O. . / The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia. In: Acta neurologica belgica. 2018 ; Vol. 118, No. 4. pp. 637–642.

Harvard

Piersma, D, Fuermaier, ABM, de Waard, D, De Deyn, PP, Davidse, RJ, de Groot, J, Doumen, MJA, Bredewoud, RA, Claesen, R, Lemstra, AW, Vermeeren, A, Ponds, R, Verhey, F, Brouwer, WH & Tucha, O 2018, 'The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia' Acta neurologica belgica, vol. 118, no. 4, pp. 637–642. https://doi.org/10.1007/s13760-018-1036-3

Standard

The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia. / Piersma, D.; Fuermaier, A. B. M.; de Waard, D.; De Deyn, P. P.; Davidse, R. J.; de Groot, J.; Doumen, M. J. A.; Bredewoud, R. A. ; Claesen, R.; Lemstra, A. W.; Vermeeren, A.; Ponds, R.; Verhey, F.; Brouwer, W. H.; Tucha, O. .

In: Acta neurologica belgica, Vol. 118, No. 4, 12.2018, p. 637–642.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Piersma D, Fuermaier ABM, de Waard D, De Deyn PP, Davidse RJ, de Groot J et al. The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia. Acta neurologica belgica. 2018 Dec;118(4):637–642. https://doi.org/10.1007/s13760-018-1036-3


BibTeX

@article{fd6e6aa568ab43e18f5454be2908fbd3,
title = "The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia",
abstract = "Since Alzheimer’s disease may affect driving performance, patients with Alzheimer’s disease are assessed on fitness to drive. On-road driving assessments are widely used, and attempts have also been made to develop strategies to assess fitness to drive in a clinical setting. Preferably, a first indication of fitness to drive is obtained quickly after diagnosis using a single test such as the Mini-Mental State Examination (MMSE). The aim of this study is to investigate whether the MMSE can be used to predict whether patients with Alzheimer’s disease will pass or fail an on-road driving assessment. Patients with Alzheimer’s disease (n = 81) participated in a comprehensive fitness-to-drive assessment which included the MMSE as well as an on-road driving assessment [PLoS One 11(2):e0149566, 2016]. MMSE cutoffs were applied as suggested by Versijpt and colleagues [Acta Neurol Belg 117(4):811–819, 2017]. All patients with Alzheimer’s disease who scored below the lower cutoff (MMSE ≤ 19) failed the on-road driving assessment. However, a third of the patients with Alzheimer’s disease who scored above the upper cutoff (MMSE ≥ 25) failed the on-road driving assessment as well. We conclude that the MMSE alone has insufficient predictive value to correctly identify fitness to drive in patients with very mild-to-mild Alzheimer’s disease implicating the need for comprehensive assessments to determine fitness to drive in a clinical setting.",
keywords = "MINI-MENTAL-STATE, PERFORMANCE, DISEASE, CONSENSUS, SAFETY",
author = "D. Piersma and Fuermaier, {A. B. M.} and {de Waard}, D. and {De Deyn}, {P. P.} and Davidse, {R. J.} and {de Groot}, J. and Doumen, {M. J. A.} and Bredewoud, {R. A.} and R. Claesen and Lemstra, {A. W.} and A. Vermeeren and R. Ponds and F. Verhey and Brouwer, {W. H.} and O. Tucha",
year = "2018",
month = "12",
doi = "10.1007/s13760-018-1036-3",
language = "English",
volume = "118",
pages = "637–642",
journal = "Acta neurologica belgica",
issn = "0300-9009",
publisher = "SPRINGER HEIDELBERG",
number = "4",

}

RIS

TY - JOUR

T1 - The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia

AU - Piersma, D.

AU - Fuermaier, A. B. M.

AU - de Waard, D.

AU - De Deyn, P. P.

AU - Davidse, R. J.

AU - de Groot, J.

AU - Doumen, M. J. A.

AU - Bredewoud, R. A.

AU - Claesen, R.

AU - Lemstra, A. W.

AU - Vermeeren, A.

AU - Ponds, R.

AU - Verhey, F.

AU - Brouwer, W. H.

AU - Tucha, O.

PY - 2018/12

Y1 - 2018/12

N2 - Since Alzheimer’s disease may affect driving performance, patients with Alzheimer’s disease are assessed on fitness to drive. On-road driving assessments are widely used, and attempts have also been made to develop strategies to assess fitness to drive in a clinical setting. Preferably, a first indication of fitness to drive is obtained quickly after diagnosis using a single test such as the Mini-Mental State Examination (MMSE). The aim of this study is to investigate whether the MMSE can be used to predict whether patients with Alzheimer’s disease will pass or fail an on-road driving assessment. Patients with Alzheimer’s disease (n = 81) participated in a comprehensive fitness-to-drive assessment which included the MMSE as well as an on-road driving assessment [PLoS One 11(2):e0149566, 2016]. MMSE cutoffs were applied as suggested by Versijpt and colleagues [Acta Neurol Belg 117(4):811–819, 2017]. All patients with Alzheimer’s disease who scored below the lower cutoff (MMSE ≤ 19) failed the on-road driving assessment. However, a third of the patients with Alzheimer’s disease who scored above the upper cutoff (MMSE ≥ 25) failed the on-road driving assessment as well. We conclude that the MMSE alone has insufficient predictive value to correctly identify fitness to drive in patients with very mild-to-mild Alzheimer’s disease implicating the need for comprehensive assessments to determine fitness to drive in a clinical setting.

AB - Since Alzheimer’s disease may affect driving performance, patients with Alzheimer’s disease are assessed on fitness to drive. On-road driving assessments are widely used, and attempts have also been made to develop strategies to assess fitness to drive in a clinical setting. Preferably, a first indication of fitness to drive is obtained quickly after diagnosis using a single test such as the Mini-Mental State Examination (MMSE). The aim of this study is to investigate whether the MMSE can be used to predict whether patients with Alzheimer’s disease will pass or fail an on-road driving assessment. Patients with Alzheimer’s disease (n = 81) participated in a comprehensive fitness-to-drive assessment which included the MMSE as well as an on-road driving assessment [PLoS One 11(2):e0149566, 2016]. MMSE cutoffs were applied as suggested by Versijpt and colleagues [Acta Neurol Belg 117(4):811–819, 2017]. All patients with Alzheimer’s disease who scored below the lower cutoff (MMSE ≤ 19) failed the on-road driving assessment. However, a third of the patients with Alzheimer’s disease who scored above the upper cutoff (MMSE ≥ 25) failed the on-road driving assessment as well. We conclude that the MMSE alone has insufficient predictive value to correctly identify fitness to drive in patients with very mild-to-mild Alzheimer’s disease implicating the need for comprehensive assessments to determine fitness to drive in a clinical setting.

KW - MINI-MENTAL-STATE

KW - PERFORMANCE

KW - DISEASE

KW - CONSENSUS

KW - SAFETY

U2 - 10.1007/s13760-018-1036-3

DO - 10.1007/s13760-018-1036-3

M3 - Article

VL - 118

SP - 637

EP - 642

JO - Acta neurologica belgica

JF - Acta neurologica belgica

SN - 0300-9009

IS - 4

ER -

ID: 66993002