The impact of surgical aortic valve replacement on quality of life: a multicenter studyZwiers-Blokzijl, F., Houterman, S., van Straten, B. H. M., Daeter, E. J., Brandon Bravo Bruinsma, G. J., Dieperink, W., Reneman, M., Keus, E., van der Horst, I. C. C. & Mariani, M., 25-Sep-2019, In : JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 27 p.
Research output: Contribution to journal › Article › Academic › peer-review
OBJECTIVES: To explore the effect of surgical aortic valve replacement on quality of life and the variance with age, particularly in patients at risk of deterioration.
METHODS: In an observational, multicenter, cohort study of routinely collected health data, patients undergoing and electively operated between January 2011 and January 2015 with pre- and postoperative quality of life data were included. Patients were classified into 3 age groups: <65, 65-79, and ≥80 years. Quality of life was measured at baseline and at 1-year follow-up using the Short-Form Health Survey-12 or SF-36. We defined a >5-point difference as a minimal clinically important difference. Multivariable linear regression analysis, with adjustment for confounders, was used to evaluate the association between age and quality of life.
RESULTS: In 899 patients, mean physical health increased from 55 to 66 and mental health from 60 to 66. A minimal clinically important decreased physical health was observed in 12% of patients aged <65 years, 16% of patients aged 65-79 years, and 22% of patients aged ≥80 years (P = .023). A decreased mental health was observed in 15% of patients aged <65 years, 22% of patients aged 65-79 years, and 24% aged ≥80 years (P = .030). Older age and a greater physical and mental score at baseline were associated with a decreased physical and mental quality of life (P < .001).
CONCLUSIONS: Patients surviving surgical aortic valve replacement on average improve in physical and mental quality of life; nonetheless, with increasing age patients are at higher risk of experiencing a deterioration.
|Number of pages||27|
|Journal||JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY|
|Publication status||E-pub ahead of print - 25-Sep-2019|