Publication

The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression: A mechanistic model of rumination

van Vugt, M. K., Hitchcock, P., Shahar, B. & Britton, W., 19-Sep-2012, In : Frontiers in Human Neuroscience. 6, 13 p., 257.

Research output: Contribution to journalArticleAcademicpeer-review

APA

van Vugt, M. K., Hitchcock, P., Shahar, B., & Britton, W. (2012). The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression: A mechanistic model of rumination. Frontiers in Human Neuroscience, 6, [257]. https://doi.org/10.3389/fnhum.2012.00257

Author

van Vugt, Marieke K. ; Hitchcock, Peter ; Shahar, Ben ; Britton, Willoughby. / The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression : A mechanistic model of rumination. In: Frontiers in Human Neuroscience. 2012 ; Vol. 6.

Harvard

van Vugt, MK, Hitchcock, P, Shahar, B & Britton, W 2012, 'The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression: A mechanistic model of rumination' Frontiers in Human Neuroscience, vol. 6, 257. https://doi.org/10.3389/fnhum.2012.00257

Standard

The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression : A mechanistic model of rumination. / van Vugt, Marieke K.; Hitchcock, Peter; Shahar, Ben; Britton, Willoughby.

In: Frontiers in Human Neuroscience, Vol. 6, 257, 19.09.2012.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

van Vugt MK, Hitchcock P, Shahar B, Britton W. The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression: A mechanistic model of rumination. Frontiers in Human Neuroscience. 2012 Sep 19;6. 257. https://doi.org/10.3389/fnhum.2012.00257


BibTeX

@article{51b77670d903408fa14af01816da1c82,
title = "The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression: A mechanistic model of rumination",
abstract = "Objectives: Converging research suggests that mindfulness training exerts its therapeutic effects on depression by reducing rumination. Theoretically, rumination is a multifaceted construct that aggregates multiple neurocognitive aspects of depression, including poor executive control, negative and overgeneral memory bias, and persistence or stickiness of negative mind states. Current measures of rumination, most often self-reports, do not capture these different aspects of ruminative tendencies, and therefore are limited in providing detailed information about the mechanisms of mindfulness. Methods: We developed new insight into the potential mechanisms of rumination, based on three model-based metrics of free recall dynamics. These three measures reflect the patterns of memory retrieval of valenced information: The probability of first recall (Pstart) which represents initial affective bias, the probability of staying with the same valence category rather than switching, which indicates strength of positive or negative association networks (Pstay); and probability of stopping (Pstop) or ending recall within a given valence, which indicates {"}drift{"} persistence or stickiness of a mind state. We investigated the effects of MBCT (N=29) vs wait-list control (N=23) on these recall dynamics in a Randomized Controlled Trial (RCT) in individuals with recurrent depression. Participants completed a standard laboratory stressor, the Trier Social Stress Test (TSST), to induce negative mood and activate ruminative tendencies. Following that, participants completed a free recall task consisting of three word lists. This assessment was conducted both before and after treatment or wait-list. Results: While MBCT participant's Pstart remained relatively stable, controls showed multiple indications of depression-related deterioration towards more negative and less positive bias. Following the intervention, MBCT participants decreased in their tendency to sustain trains of negative words and increased their tendency to sustain trains of positive words. Conversely, controls showed the opposite tendency: controls stayed in trains of negative words for longer, and stayed in trains of positive words for less time relative to T1 scores. MBCT participants tended to stop recall less often with negative words, which indicates less persistence or stickiness of negatively-valenced mental context. Conclusion: MBCT participants showed a decrease in patterns that may perpetuate rumination on all three types of recall dynamics (Pstart, Pstay and Pstop), compared to controls. MBCT may weaken the strength of self-perpetuating negative associations networks that are responsible for the persistent and {"}sticky{"} negative mind states observed in depression, and increase in positive associations that are lacking in depression. This study also offers a novel, objective method of measuring several indices of ruminative tendencies indicative of the underlying mechanisms of rumination. {\circledC} 2012 Van vugt, Hitchcock, Shahar and Britton.",
keywords = "memory, emotional processing, mindfulness, free recall, RANDOMIZED CONTROLLED-TRIAL, CEREBRAL-BLOOD-FLOW, OVERGENERAL AUTOBIOGRAPHICAL MEMORY, COGNITIVE SCIENCE PERSPECTIVE, NATIONAL COMORBIDITY SURVEY, RECURRENT MAJOR DEPRESSION, STRESS REDUCTION PROGRAM, LEVEL CORTISOL TREATMENT, EMOTION REGULATION, AFFECTIVE NEUROSCIENCE",
author = "{van Vugt}, {Marieke K.} and Peter Hitchcock and Ben Shahar and Willoughby Britton",
year = "2012",
month = "9",
day = "19",
doi = "10.3389/fnhum.2012.00257",
language = "English",
volume = "6",
journal = "Frontiers in Human Neuroscience",
issn = "1662-5161",
publisher = "Frontiers Media S.A.",

}

RIS

TY - JOUR

T1 - The effects of mindfulness-based cognitive therapy on affective memory recall dynamics in depression

T2 - A mechanistic model of rumination

AU - van Vugt, Marieke K.

AU - Hitchcock, Peter

AU - Shahar, Ben

AU - Britton, Willoughby

PY - 2012/9/19

Y1 - 2012/9/19

N2 - Objectives: Converging research suggests that mindfulness training exerts its therapeutic effects on depression by reducing rumination. Theoretically, rumination is a multifaceted construct that aggregates multiple neurocognitive aspects of depression, including poor executive control, negative and overgeneral memory bias, and persistence or stickiness of negative mind states. Current measures of rumination, most often self-reports, do not capture these different aspects of ruminative tendencies, and therefore are limited in providing detailed information about the mechanisms of mindfulness. Methods: We developed new insight into the potential mechanisms of rumination, based on three model-based metrics of free recall dynamics. These three measures reflect the patterns of memory retrieval of valenced information: The probability of first recall (Pstart) which represents initial affective bias, the probability of staying with the same valence category rather than switching, which indicates strength of positive or negative association networks (Pstay); and probability of stopping (Pstop) or ending recall within a given valence, which indicates "drift" persistence or stickiness of a mind state. We investigated the effects of MBCT (N=29) vs wait-list control (N=23) on these recall dynamics in a Randomized Controlled Trial (RCT) in individuals with recurrent depression. Participants completed a standard laboratory stressor, the Trier Social Stress Test (TSST), to induce negative mood and activate ruminative tendencies. Following that, participants completed a free recall task consisting of three word lists. This assessment was conducted both before and after treatment or wait-list. Results: While MBCT participant's Pstart remained relatively stable, controls showed multiple indications of depression-related deterioration towards more negative and less positive bias. Following the intervention, MBCT participants decreased in their tendency to sustain trains of negative words and increased their tendency to sustain trains of positive words. Conversely, controls showed the opposite tendency: controls stayed in trains of negative words for longer, and stayed in trains of positive words for less time relative to T1 scores. MBCT participants tended to stop recall less often with negative words, which indicates less persistence or stickiness of negatively-valenced mental context. Conclusion: MBCT participants showed a decrease in patterns that may perpetuate rumination on all three types of recall dynamics (Pstart, Pstay and Pstop), compared to controls. MBCT may weaken the strength of self-perpetuating negative associations networks that are responsible for the persistent and "sticky" negative mind states observed in depression, and increase in positive associations that are lacking in depression. This study also offers a novel, objective method of measuring several indices of ruminative tendencies indicative of the underlying mechanisms of rumination. © 2012 Van vugt, Hitchcock, Shahar and Britton.

AB - Objectives: Converging research suggests that mindfulness training exerts its therapeutic effects on depression by reducing rumination. Theoretically, rumination is a multifaceted construct that aggregates multiple neurocognitive aspects of depression, including poor executive control, negative and overgeneral memory bias, and persistence or stickiness of negative mind states. Current measures of rumination, most often self-reports, do not capture these different aspects of ruminative tendencies, and therefore are limited in providing detailed information about the mechanisms of mindfulness. Methods: We developed new insight into the potential mechanisms of rumination, based on three model-based metrics of free recall dynamics. These three measures reflect the patterns of memory retrieval of valenced information: The probability of first recall (Pstart) which represents initial affective bias, the probability of staying with the same valence category rather than switching, which indicates strength of positive or negative association networks (Pstay); and probability of stopping (Pstop) or ending recall within a given valence, which indicates "drift" persistence or stickiness of a mind state. We investigated the effects of MBCT (N=29) vs wait-list control (N=23) on these recall dynamics in a Randomized Controlled Trial (RCT) in individuals with recurrent depression. Participants completed a standard laboratory stressor, the Trier Social Stress Test (TSST), to induce negative mood and activate ruminative tendencies. Following that, participants completed a free recall task consisting of three word lists. This assessment was conducted both before and after treatment or wait-list. Results: While MBCT participant's Pstart remained relatively stable, controls showed multiple indications of depression-related deterioration towards more negative and less positive bias. Following the intervention, MBCT participants decreased in their tendency to sustain trains of negative words and increased their tendency to sustain trains of positive words. Conversely, controls showed the opposite tendency: controls stayed in trains of negative words for longer, and stayed in trains of positive words for less time relative to T1 scores. MBCT participants tended to stop recall less often with negative words, which indicates less persistence or stickiness of negatively-valenced mental context. Conclusion: MBCT participants showed a decrease in patterns that may perpetuate rumination on all three types of recall dynamics (Pstart, Pstay and Pstop), compared to controls. MBCT may weaken the strength of self-perpetuating negative associations networks that are responsible for the persistent and "sticky" negative mind states observed in depression, and increase in positive associations that are lacking in depression. This study also offers a novel, objective method of measuring several indices of ruminative tendencies indicative of the underlying mechanisms of rumination. © 2012 Van vugt, Hitchcock, Shahar and Britton.

KW - memory

KW - emotional processing

KW - mindfulness

KW - free recall

KW - RANDOMIZED CONTROLLED-TRIAL

KW - CEREBRAL-BLOOD-FLOW

KW - OVERGENERAL AUTOBIOGRAPHICAL MEMORY

KW - COGNITIVE SCIENCE PERSPECTIVE

KW - NATIONAL COMORBIDITY SURVEY

KW - RECURRENT MAJOR DEPRESSION

KW - STRESS REDUCTION PROGRAM

KW - LEVEL CORTISOL TREATMENT

KW - EMOTION REGULATION

KW - AFFECTIVE NEUROSCIENCE

U2 - 10.3389/fnhum.2012.00257

DO - 10.3389/fnhum.2012.00257

M3 - Article

VL - 6

JO - Frontiers in Human Neuroscience

JF - Frontiers in Human Neuroscience

SN - 1662-5161

M1 - 257

ER -

ID: 5672977