The discovery of new isocyanide-based multi-component reactionsDömling, A., 1-Jun-2000, In : Current Opinion in Chemical Biology. 4, 3, p. 318-323 6 p.
Research output: Contribution to journal › Book/Film/Article review › Professional
Multi-component reactions are finding increasing use in the discovery process of new drugs and agrochemicals. Some years ago they were considered as highly exotic types of organic reactions. Recently, many groups have realized that the field of multi-component reactions is full of new opportunities. These comprise fast and efficient production of small-molecular-weight compound libraries, highly atom-economic chemistry, very large chemical libraries, improvements in total synthesis, and applications in bioconjugate chemistry, as well as in related fields (e.g. chemical biology).
|Number of pages||6|
|Journal||Current Opinion in Chemical Biology|
|Publication status||Published - 1-Jun-2000|
- alpha amino acid, benzodiazepine derivative, bleomycin, cystothiazole F, dihydroquinoline derivative, karnamycin B1, piperazine derivative, thiazole derivative, thiostrepton, tubulysine, unclassified drug, chemical reaction, drug research, drug screening, organic chemistry, review