Synthetic Minimal Cell: Self-Reproduction of the Boundary LayerExterkate, M. & Driessen, A. J. M., 31-Mar-2019, In : ACS Omega. 4, 3, p. 5293-5303 11 p., 02955.
Research output: Contribution to journal › Article › Academic › peer-review
A critical aspect in the bottom-up construction of a synthetic minimal cell is to develop an entity that is capable of self-reproduction. A key role in this process is the expansion and division of the boundary layer that surrounds the compartment, a process in which content loss has to be avoided and the barrier function maintained. Here, we describe the latest developments regarding self-reproduction of a boundary layer with a focus on the growth and division of phospholipid-based membranes in the context of a synthetic minimal cell.
|Number of pages||11|
|Publication status||Published - 31-Mar-2019|
- synthetic biology, minimal cell, SELF-REPRODUCTION, MEMBRANE PHOSPHOLIPID-SYNTHESIS, IN-VITRO RECONSTITUTION, FATTY-ACID SYNTHASES, ESCHERICHIA-COLI, FLIP-FLOP, PROTEIN TRANSLOCATION, BACTERIAL LIPIDS, DIVISION, VESICLES, MODEL