Publication
Synthesis of labile all-trans-7,8,7′,8′-bis-acetylenic carotenoids by bi-directional Horner-Wadsworth-Emmons condensation
Vaz, B., Fontán, N., Castiñeira, M., Álvarez, R. & De Lera, Á. R., 14-Mar-2015, In : Organic and Biomolecular Chemistry. 13, 10, p. 3024-3031 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Documents
- Synthesis of labile all-trans-7,8,7′,8′-bis-acetylenic carotenoids by bi-directional Horner–Wadsworth–Emmons condensation
Final publisher's version, 576 KB, PDF document
DOI
A new stereoselective synthesis of the C40-bis-acetylenic carotenoids all-trans-(3R,3′R)-alloxanthin and all-trans-3,4,7,8,3′,4′,7′,8′-octadehydro-β,β-carotene, both compounds featuring a stereochemically labile C7-C10 enyne, based on a bi-directional Horner-Wadsworth-Emmons (HWE) reaction of a C15-phosphonate and a central C10-dialdehyde, is reported. The triene unit of the latter fragment was synthesized using the acyclic metathesis/dimerization reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 3024-3031 |
| Number of pages | 8 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 13 |
| Issue number | 10 |
| Publication status | Published - 14-Mar-2015 |
| Externally published | Yes |
ID: 134759319