Symptom-based questionnaire for differentiating COPD and asthma

Tinkelman, D. G., Price, D. B., Nordyke, R. J., Halbert, R. J., Isonaka, S., Nonikov, D., Juniper, E. F., Freeman, D., Hausen, T., Levy, M. L., Ostrem, A., van der Molen, T. & van Schayck, C. P., 2006, In : Respiration. 73, 3, p. 296-305 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

  • David G. Tinkelman
  • David B. Price
  • Robert J. Nordyke
  • R. J. Halbert
  • Sharon Isonaka
  • Dmitry Nonikov
  • Elizabeth F. Juniper
  • Daryl Freeman
  • Thomas Hausen
  • Mark L. Levy
  • Anders Ostrem
  • Thys van der Molen
  • Constant P. van Schayck

Background: Many patients with obstructive lung disease (OLD) carry an inaccurate diagnostic label. Symptom-based questionnaires could identify persons likely to need spirometry. Objectives: We prospectively tested questions derived from a comprehensive literature review and an international Delphi panel to help identify chronic OLD (COPD) in persons with prior evidence of OLD. Methods: Subjects were recruited via random mailing to primary-care practices in Aberdeen, Scotland, and Denver, Colorado. Persons aged 40 and older reporting any prior diagnosis of OLD or any respiratory medications in the past year were enrolled. Participants answered 54 questions covering demographics and symptoms and underwent spirometry with reversibility testing. A study diagnosis of COPD was defined by fixed airway obstruction as measured by post-bronchodilator FEV1/FVC

Original languageEnglish
Pages (from-to)296-305
Number of pages10
Issue number3
Publication statusPublished - 2006


  • asthma, chronic obstructive pulmonary disease (COPD), diagnosis, primary care, questionnaires, spirometry, validation studies, OBSTRUCTIVE PULMONARY-DISEASE, GENERAL-PRACTICE, RESPIRATORY SYMPTOMS, EUROPEAN-COMMUNITY, DIAGNOSIS, PREVALENCE, GUIDELINES, MEDICATION

ID: 1535768