Studying the gut virome in the metagenomic era: challenges and perspectivesGarmaeva, S., Sinha, T., Kurilshikov, A., Wijmenga, C., Fu, J. & Zhernakova, S., 28-Oct-2019, In : BMC Biology. 17, 1, 14 p., 84.
Research output: Contribution to journal › Review article › Academic › peer-review
The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of humangut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review, we focus on what is known about the role of bacteriophages in human health and the technical challenges involved in studying the gut virome, of which they are a major component. Lastly, we discuss what can be learned from studies of bacteriophages in other ecosystems.
|Number of pages||14|
|Publication status||Published - 28-Oct-2019|
- VIRUS-LIKE PARTICLES, BACTERIOPHAGE-LAMBDA, BACTERIAL MICROBIOME, FECAL MICROBIOTA, MARINE VIRUSES, PHAGE, EVOLUTION, DYNAMICS, GENOMES, PROPHAGES