Publication

Spatio-temporal dynamics of dengue and chikungunya: Understanding arboviral transmission patterns to improve surveillance and control

Vincenti Gonzalez, M. F., 2018, [Groningen]: University of Groningen. 310 p.

Research output: ThesisThesis fully internal (DIV)Academic

Copy link to clipboard

Documents

  • Title and contents

    Final publisher's version, 343 KB, PDF-document

  • Chapter 1

    Final publisher's version, 825 KB, PDF-document

  • Chapter 2

    Final publisher's version, 2 MB, PDF-document

  • Chapter 3

    Final publisher's version, 1 MB, PDF-document

    Embargo ends: 12/12/2019

  • Chapter 4

    Final publisher's version, 2 MB, PDF-document

    Embargo ends: 12/12/2019

  • Chapter 5

    Final publisher's version, 3 MB, PDF-document

  • supplementary_chapter5_video1

    Final publisher's version, 5 MB, video/quicktime

  • Chapter 6

    Final publisher's version, 4 MB, PDF-document

    Embargo ends: 12/12/2019

  • Chapter 7

    Final publisher's version, 3 MB, PDF-document

  • Chapter 8

    Final publisher's version, 1 MB, PDF-document

    Embargo ends: 12/12/2019

  • Chapter 9

    Final publisher's version, 1 MB, PDF-document

  • Chapter 10

    Final publisher's version, 2 MB, PDF-document

    Embargo ends: 12/12/2019

  • Chapter 11

    Final publisher's version, 1 MB, PDF-document

  • Chapter 12 Appendix

    Final publisher's version, 6 MB, PDF-document

  • Complete thesis

    Final publisher's version, 18 MB, PDF-document

    Embargo ends: 12/12/2019

  • Propositions

    Final publisher's version, 89 KB, PDF-document

Dengue is one of the fastest spreading vector-borne diseases (VBD) worldwide that poses an important burden on concerned populations. In Venezuela, control of this infection and of its mosquito vector (Aedes aegypti) has proven challenging. Currently, dengue control methods rely mostly on vector reduction; however, these activities have demonstrated to be largely unsuccessful. Globally, there is a call for action to change how surveillance and control of dengue and other VBD (such as chikungunya and Zika), are currently performed since the classical approach seems not sufficient to effectively reduce the morbidity and mortality caused by these diseases.

The research described in this thesis is focused on the identification and characterization of the spatial and temporal determinants of dengue virus (DENV) and chikungunya virus (CHIKV) transmission. The thesis emphasizes the spatial and spatio-temporal patterns of disease prevalence/incidence and their determinants and the influence of climate fluctuations on the temporal patterns of dengue.

The results obtained in this thesis provide important evidence about the dengue and chikungunya spatial and temporal patterns in Venezuela. It also highpoints the relevance that geographical information systems and spatial analysis have on the surveillance and control of vector-borne diseases. The elaboration of a combined program of control of mosquito-borne diseases which includes the spatial and temporal analysis of the patterns of disease transmission will help to identify the most vulnerable and high-risk zones for transmission and may reduce morbidity, mortality and the burden of these diseases on the population and health care centers.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Supervisors/Advisors
  • Friedrich, Alex, Supervisor
  • Grillet, Maria Eugenia, Supervisor, External person
  • Tami, Adriana, Co-supervisor
  • Werf, van der, Tjipke, Assessment committee
  • Cotrim Segurado, A. A., Assessment committee, External person
  • de Lamballerie, Xavier, Assessment committee, External person
Award date12-Dec-2018
Place of Publication[Groningen]
Publisher
Print ISBNs978-94-034-1234-4
Electronic ISBNs978-94-034-1233-7
Publication statusPublished - 2018

View graph of relations

Download statistics

No data available

ID: 71851520