Publication

Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies

Kuiper, J. S., Zuidersma, M., Oude Voshaar, R., Zuidema, S., van den Heuvel, E. R., Stolk, R. P. & Smidt, N., Jul-2015, In : Ageing Research Reviews. 22, p. 39-57 19 p.

Research output: Contribution to journalReview articleAcademicpeer-review

It is unclear to what extent poor social relationships are related to the development of dementia. A comprehensive systematic literature search identified 19 longitudinal cohort studies investigating the association between various social relationship factors and incident dementia in the general population. Relative risks (RRs) with 95% confidence intervals (CIs) were pooled using random-effects meta-analysis. Low social participation (RR: 1.41 (95% CI: 1.13-1.75)), less frequent social contact (RR: 1.57 (95% CI: 1.32-1.85)), and more loneliness (RR: 1.58 (95% CI: 1.19-2.09)) were statistically significant associated with incident dementia. The results of the association between social network size and dementia were inconsistent. No statistically significant association was found for low satisfaction with social network and the onset of dementia (RR: 1.25(95% CI: 0.96-1.62). We conclude that social relationship factors that represent a lack of social interaction are associated with incident dementia. The strength of the associations between poor social interaction and incident dementia is comparable with other well-established risk factors for dementia, including low education attainment, physical inactivity, and late-life depression. (C) 2015 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)39-57
Number of pages19
JournalAgeing Research Reviews
Volume22
Publication statusPublished - Jul-2015

    Keywords

  • Dementia, Social network, Social participation, Loneliness, Social contact, Social relationships, MILD COGNITIVE IMPAIRMENT, LIFE-STYLE FACTORS, ALZHEIMERS-DISEASE, LEISURE ACTIVITIES, GLOBAL PREVALENCE, DECLINE, NETWORK, ENGAGEMENT, PREVENTION, PROGNOSIS

ID: 21057355