Publication

Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness

Buunk, A., Spikman, J. M., Veenstra, W. S., van Laar, P. J., Metzemaekers, J. D. M., van Dijk, J. M. C., Meiners, L. C. & Groen, R. J. M., Aug-2017, In : Neuropsychologia. 103, p. 131-139 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Buunk, A., Spikman, J. M., Veenstra, W. S., van Laar, P. J., Metzemaekers, J. D. M., van Dijk, J. M. C., ... Groen, R. J. M. (2017). Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness. Neuropsychologia, 103, 131-139. https://doi.org/10.1016/j.neuropsychologia.2017.07.015

Author

Buunk, Anne ; Spikman, Jacoba M. ; Veenstra, Wencke S. ; van Laar, Peter Jan ; Metzemaekers, Jan D.M. ; van Dijk, J. Marc C. ; Meiners, Linda C. ; Groen, Rob J.M. / Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness. In: Neuropsychologia. 2017 ; Vol. 103. pp. 131-139.

Harvard

Buunk, A, Spikman, JM, Veenstra, WS, van Laar, PJ, Metzemaekers, JDM, van Dijk, JMC, Meiners, LC & Groen, RJM 2017, 'Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness', Neuropsychologia, vol. 103, pp. 131-139. https://doi.org/10.1016/j.neuropsychologia.2017.07.015

Standard

Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness. / Buunk, Anne; Spikman, Jacoba M.; Veenstra, Wencke S.; van Laar, Peter Jan; Metzemaekers, Jan D.M.; van Dijk, J. Marc C.; Meiners, Linda C.; Groen, Rob J.M.

In: Neuropsychologia, Vol. 103, 08.2017, p. 131-139.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Buunk A, Spikman JM, Veenstra WS, van Laar PJ, Metzemaekers JDM, van Dijk JMC et al. Social cognition impairments after aneurysmal subarachnoid haemorrhage: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness. Neuropsychologia. 2017 Aug;103:131-139. https://doi.org/10.1016/j.neuropsychologia.2017.07.015


BibTeX

@article{cf66ded84bb742c3a4c4922f9a00d7cf,
title = "Social cognition impairments after aneurysmal subarachnoid haemorrhage:: associations with deficits in interpersonal behaviour, apathy and impaired self-awareness",
abstract = "Behavioural disturbances are frequently found after aneurysmal subarachnoid haemorrhage (aSAH). Social cognition impairments have been suggested as a possible underlying mechanism for behavioural problems. Also, aSAH is likely to result in damage affecting frontal-subcortical circuits underlying social cognition. Therefore, we aimed to investigate social cognition after aSAH and its associations with behavioural problems (deficits in interpersonal behaviour, apathy, and impaired self-awareness) and focal as well as diffuse brain damage. 88 aSAH patients (in the subacute phase post-aSAH) and 60 age-, sex- and education-matched healthy controls participated. Tasks for emotion recognition, Theory of Mind (ToM), and empathy as well as questionnaires were used. Cortical infarctions in frontal and non-frontal areas on MRI, aneurysm circulation and aSAH-related events were taken into account. Compared to healthy controls, aSAH patients performed significantly worse on tasks for emotion recognition, ToM and empathy. Poor performance on ToM and emotion recognition was associated with proxy-ratings indicating impaired interpersonal behaviour and apathy and with indications of impaired self-awareness. No associations were found between deficits in social cognition and frontal or non-frontal cortical lesions on MRI. Also, aneurysm circulation and aSAH-related events such as hydrocephalus, vasospasm, and treatment method did not explain why and how social cognitive deficits did occur after aSAH. In conclusion, emotion recognition, ToM and empathy were clearly impaired in aSAH patients and these deficits were related to apathy and deficits in interpersonal behaviour as reported by proxies and to impaired self-awareness. This association strengthens the assumption of impaired social cognition as an underlying construct of behavioural problems after aSAH. Consequently, social cognition tests and proxy-ratings should be used in clinical practice, irrespective of lesion location on MRI or aneurysm circulation, to improve the detection and treatment of apathy and deficits in interpersonal behaviour after aSAH.",
keywords = "Social cognition, Subarachnoid haemorrhage, Apathy, Self-awareness, Magnetic resonance imaging, TRAUMATIC BRAIN-INJURY, DELAYED CEREBRAL-ISCHEMIA, QUALITY-OF-LIFE, EMOTION RECOGNITION, PREFRONTAL LESIONS, ASPERGER-SYNDROME, MIND IMPAIRMENTS, CLINICAL-TRIALS, STROKE PATIENTS, ACQUIRED THEORY",
author = "Anne Buunk and Spikman, {Jacoba M.} and Veenstra, {Wencke S.} and {van Laar}, {Peter Jan} and Metzemaekers, {Jan D.M.} and {van Dijk}, {J. Marc C.} and Meiners, {Linda C.} and Groen, {Rob J.M.}",
year = "2017",
month = "8",
doi = "10.1016/j.neuropsychologia.2017.07.015",
language = "English",
volume = "103",
pages = "131--139",
journal = "Neuropsychologia",
issn = "0028-3932",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

}

RIS

TY - JOUR

T1 - Social cognition impairments after aneurysmal subarachnoid haemorrhage:

T2 - associations with deficits in interpersonal behaviour, apathy and impaired self-awareness

AU - Buunk, Anne

AU - Spikman, Jacoba M.

AU - Veenstra, Wencke S.

AU - van Laar, Peter Jan

AU - Metzemaekers, Jan D.M.

AU - van Dijk, J. Marc C.

AU - Meiners, Linda C.

AU - Groen, Rob J.M.

PY - 2017/8

Y1 - 2017/8

N2 - Behavioural disturbances are frequently found after aneurysmal subarachnoid haemorrhage (aSAH). Social cognition impairments have been suggested as a possible underlying mechanism for behavioural problems. Also, aSAH is likely to result in damage affecting frontal-subcortical circuits underlying social cognition. Therefore, we aimed to investigate social cognition after aSAH and its associations with behavioural problems (deficits in interpersonal behaviour, apathy, and impaired self-awareness) and focal as well as diffuse brain damage. 88 aSAH patients (in the subacute phase post-aSAH) and 60 age-, sex- and education-matched healthy controls participated. Tasks for emotion recognition, Theory of Mind (ToM), and empathy as well as questionnaires were used. Cortical infarctions in frontal and non-frontal areas on MRI, aneurysm circulation and aSAH-related events were taken into account. Compared to healthy controls, aSAH patients performed significantly worse on tasks for emotion recognition, ToM and empathy. Poor performance on ToM and emotion recognition was associated with proxy-ratings indicating impaired interpersonal behaviour and apathy and with indications of impaired self-awareness. No associations were found between deficits in social cognition and frontal or non-frontal cortical lesions on MRI. Also, aneurysm circulation and aSAH-related events such as hydrocephalus, vasospasm, and treatment method did not explain why and how social cognitive deficits did occur after aSAH. In conclusion, emotion recognition, ToM and empathy were clearly impaired in aSAH patients and these deficits were related to apathy and deficits in interpersonal behaviour as reported by proxies and to impaired self-awareness. This association strengthens the assumption of impaired social cognition as an underlying construct of behavioural problems after aSAH. Consequently, social cognition tests and proxy-ratings should be used in clinical practice, irrespective of lesion location on MRI or aneurysm circulation, to improve the detection and treatment of apathy and deficits in interpersonal behaviour after aSAH.

AB - Behavioural disturbances are frequently found after aneurysmal subarachnoid haemorrhage (aSAH). Social cognition impairments have been suggested as a possible underlying mechanism for behavioural problems. Also, aSAH is likely to result in damage affecting frontal-subcortical circuits underlying social cognition. Therefore, we aimed to investigate social cognition after aSAH and its associations with behavioural problems (deficits in interpersonal behaviour, apathy, and impaired self-awareness) and focal as well as diffuse brain damage. 88 aSAH patients (in the subacute phase post-aSAH) and 60 age-, sex- and education-matched healthy controls participated. Tasks for emotion recognition, Theory of Mind (ToM), and empathy as well as questionnaires were used. Cortical infarctions in frontal and non-frontal areas on MRI, aneurysm circulation and aSAH-related events were taken into account. Compared to healthy controls, aSAH patients performed significantly worse on tasks for emotion recognition, ToM and empathy. Poor performance on ToM and emotion recognition was associated with proxy-ratings indicating impaired interpersonal behaviour and apathy and with indications of impaired self-awareness. No associations were found between deficits in social cognition and frontal or non-frontal cortical lesions on MRI. Also, aneurysm circulation and aSAH-related events such as hydrocephalus, vasospasm, and treatment method did not explain why and how social cognitive deficits did occur after aSAH. In conclusion, emotion recognition, ToM and empathy were clearly impaired in aSAH patients and these deficits were related to apathy and deficits in interpersonal behaviour as reported by proxies and to impaired self-awareness. This association strengthens the assumption of impaired social cognition as an underlying construct of behavioural problems after aSAH. Consequently, social cognition tests and proxy-ratings should be used in clinical practice, irrespective of lesion location on MRI or aneurysm circulation, to improve the detection and treatment of apathy and deficits in interpersonal behaviour after aSAH.

KW - Social cognition

KW - Subarachnoid haemorrhage

KW - Apathy

KW - Self-awareness

KW - Magnetic resonance imaging

KW - TRAUMATIC BRAIN-INJURY

KW - DELAYED CEREBRAL-ISCHEMIA

KW - QUALITY-OF-LIFE

KW - EMOTION RECOGNITION

KW - PREFRONTAL LESIONS

KW - ASPERGER-SYNDROME

KW - MIND IMPAIRMENTS

KW - CLINICAL-TRIALS

KW - STROKE PATIENTS

KW - ACQUIRED THEORY

U2 - 10.1016/j.neuropsychologia.2017.07.015

DO - 10.1016/j.neuropsychologia.2017.07.015

M3 - Article

C2 - 28723344

VL - 103

SP - 131

EP - 139

JO - Neuropsychologia

JF - Neuropsychologia

SN - 0028-3932

ER -

ID: 44544077