Small Molecule PET-RadiopharmaceuticalsElsinga, P. H. & Dierckx, R. A. J. O., Apr-2014, In : Current Pharmaceutical Design. 20, 14, p. 2268-2274 7 p.
Research output: Contribution to journal › Article › Academic › peer-review
This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in C-11 and F-18-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.
|Number of pages||7|
|Journal||Current Pharmaceutical Design|
|Publication status||Published - Apr-2014|
- PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18, POSITRON-EMISSION-TOMOGRAPHY, NONSPECIFIC-BINDING, CHEMISTRY, MONOXIDE