Small Molecule PET-Radiopharmaceuticals

Elsinga, P. H. & Dierckx, R. A. J. O., Apr-2014, In : Current Pharmaceutical Design. 20, 14, p. 2268-2274 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in C-11 and F-18-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.

Original languageEnglish
Pages (from-to)2268-2274
Number of pages7
JournalCurrent Pharmaceutical Design
Issue number14
Publication statusPublished - Apr-2014


  • PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18, POSITRON-EMISSION-TOMOGRAPHY, NONSPECIFIC-BINDING, CHEMISTRY, MONOXIDE

ID: 16387028