Publication

Sleep deprivation increases threat beliefs in human fear conditioning

Zenses, A-K., Lenaert, B., Peigneux, P., Beckers, T. & Boddez, Y., Jun-2020, In : Journal of Sleep Research. 29, 3, 9 p., 12873.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Zenses, A-K., Lenaert, B., Peigneux, P., Beckers, T., & Boddez, Y. (2020). Sleep deprivation increases threat beliefs in human fear conditioning. Journal of Sleep Research, 29(3), [12873]. https://doi.org/10.1111/jsr.12873

Author

Zenses, Ann-Kathrin ; Lenaert, Bert ; Peigneux, Philippe ; Beckers, Tom ; Boddez, Yannick. / Sleep deprivation increases threat beliefs in human fear conditioning. In: Journal of Sleep Research. 2020 ; Vol. 29, No. 3.

Harvard

Zenses, A-K, Lenaert, B, Peigneux, P, Beckers, T & Boddez, Y 2020, 'Sleep deprivation increases threat beliefs in human fear conditioning', Journal of Sleep Research, vol. 29, no. 3, 12873. https://doi.org/10.1111/jsr.12873

Standard

Sleep deprivation increases threat beliefs in human fear conditioning. / Zenses, Ann-Kathrin; Lenaert, Bert; Peigneux, Philippe; Beckers, Tom; Boddez, Yannick.

In: Journal of Sleep Research, Vol. 29, No. 3, 12873, 06.2020.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Zenses A-K, Lenaert B, Peigneux P, Beckers T, Boddez Y. Sleep deprivation increases threat beliefs in human fear conditioning. Journal of Sleep Research. 2020 Jun;29(3). 12873. https://doi.org/10.1111/jsr.12873


BibTeX

@article{144c167102824a409051a01dbeabf58b,
title = "Sleep deprivation increases threat beliefs in human fear conditioning",
abstract = "Sleep disturbances and anxiety disorders exhibit high comorbidity levels, but it remains unclear whether sleep problems are causes or consequences of increased anxiety. To experimentally probe the aetiological role of sleep disturbances in anxiety, we investigated in healthy participants how total sleep deprivation influences fear expression in a conditioning paradigm. In a fear conditioning procedure, one face stimulus (conditioned stimulus [CS+]) was paired with electric shock, whereas another face stimulus was not (unpaired stimulus [CS-]). Fear expression was tested the next morning using the two face stimuli from the training phase and a generalization stimulus (i.e. a morph between the CS+ and CS- stimuli). Between fear conditioning and test, participants were either kept awake in the laboratory for 12 hr (n = 20) or had a night of sleep at home (n = 20). Irrespective of stimulus type, subjective threat expectancies, but not skin conductance responses, were enhanced after sleep deprivation, relative to regular sleep. These results suggest that sleep disturbances may play a role in anxiety disorders by increasing perceived threat.",
keywords = "associative learning, generalization, safety learning, sleep quality, ANXIETY DISORDERS, STIMULUS-GENERALIZATION, OVERGENERALIZATION, CONSOLIDATION, DISTURBANCE, MODEL, SHAPE",
author = "Ann-Kathrin Zenses and Bert Lenaert and Philippe Peigneux and Tom Beckers and Yannick Boddez",
year = "2020",
month = "6",
doi = "10.1111/jsr.12873",
language = "English",
volume = "29",
journal = "Journal of Sleep Research",
issn = "0962-1105",
publisher = "Wiley",
number = "3",

}

RIS

TY - JOUR

T1 - Sleep deprivation increases threat beliefs in human fear conditioning

AU - Zenses, Ann-Kathrin

AU - Lenaert, Bert

AU - Peigneux, Philippe

AU - Beckers, Tom

AU - Boddez, Yannick

PY - 2020/6

Y1 - 2020/6

N2 - Sleep disturbances and anxiety disorders exhibit high comorbidity levels, but it remains unclear whether sleep problems are causes or consequences of increased anxiety. To experimentally probe the aetiological role of sleep disturbances in anxiety, we investigated in healthy participants how total sleep deprivation influences fear expression in a conditioning paradigm. In a fear conditioning procedure, one face stimulus (conditioned stimulus [CS+]) was paired with electric shock, whereas another face stimulus was not (unpaired stimulus [CS-]). Fear expression was tested the next morning using the two face stimuli from the training phase and a generalization stimulus (i.e. a morph between the CS+ and CS- stimuli). Between fear conditioning and test, participants were either kept awake in the laboratory for 12 hr (n = 20) or had a night of sleep at home (n = 20). Irrespective of stimulus type, subjective threat expectancies, but not skin conductance responses, were enhanced after sleep deprivation, relative to regular sleep. These results suggest that sleep disturbances may play a role in anxiety disorders by increasing perceived threat.

AB - Sleep disturbances and anxiety disorders exhibit high comorbidity levels, but it remains unclear whether sleep problems are causes or consequences of increased anxiety. To experimentally probe the aetiological role of sleep disturbances in anxiety, we investigated in healthy participants how total sleep deprivation influences fear expression in a conditioning paradigm. In a fear conditioning procedure, one face stimulus (conditioned stimulus [CS+]) was paired with electric shock, whereas another face stimulus was not (unpaired stimulus [CS-]). Fear expression was tested the next morning using the two face stimuli from the training phase and a generalization stimulus (i.e. a morph between the CS+ and CS- stimuli). Between fear conditioning and test, participants were either kept awake in the laboratory for 12 hr (n = 20) or had a night of sleep at home (n = 20). Irrespective of stimulus type, subjective threat expectancies, but not skin conductance responses, were enhanced after sleep deprivation, relative to regular sleep. These results suggest that sleep disturbances may play a role in anxiety disorders by increasing perceived threat.

KW - associative learning

KW - generalization

KW - safety learning

KW - sleep quality

KW - ANXIETY DISORDERS

KW - STIMULUS-GENERALIZATION

KW - OVERGENERALIZATION

KW - CONSOLIDATION

KW - DISTURBANCE

KW - MODEL

KW - SHAPE

U2 - 10.1111/jsr.12873

DO - 10.1111/jsr.12873

M3 - Article

VL - 29

JO - Journal of Sleep Research

JF - Journal of Sleep Research

SN - 0962-1105

IS - 3

M1 - 12873

ER -

ID: 82489634