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Sjögren's syndrome is not a risk factor for periodontal disease: a systematic review

Maarse, F., Jager, D. H. J., Alterch, S., Korfage, A., Forouzanfar, T., Vissink, A. & Brand, H. S., 30-Aug-2019, In : Clinical and Experimental Rheumatology. 37 Suppl 118, 3, p. 225-233 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

OBJECTIVES: Sjögren's syndrome (SS) is an autoimmune disorder causing irreversible damage to the exocrine glands. Evidence whether SS patients are at a higher risk to develop periodontal disease is conflicting. Therefore, we systematically reviewed the literature on the prevalence of periodontal disease in patients with SS.

METHODS: Searches were performed in MEDLINE and CENTRAL databases on prevalence of periodontal diseases in SS. Meta-analyses were performed for gingival index (GI), plaque index (PI), probing pocket depth (PPD), clinical attachment level (CAL), DMFT and DMFS (Decayed Missing Filled Teeth, respectively, Surfaces).

RESULTS: Out of 512 studies, 10 studies were eligible for quantitative synthesis. Meta-analyses of the data indicated that in SS patients CAL, GI, PPD and PI are comparable to controls. DMFT and DMFS values were higher in SS patients than controls.

CONCLUSIONS: No significant differences in the GI, PI, CAL, and PPD were observed in patients with SS compared to controls. These results indicate that there is no evidence of a higher risk for periodontal disease in patients with SS, while SS patients are more susceptible to caries compared to non-SS patients.

Original languageEnglish
Pages (from-to)225-233
Number of pages9
JournalClinical and Experimental Rheumatology
Volume37 Suppl 118
Issue number3
Publication statusPublished - 30-Aug-2019

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