Publication

Short-term surgical complications after radical hysterectomy - a nationwide cohort study

Wenzel, H. H. B., Kruitwagen, R. F. P. M., Nijman, H. W., Bekkers, R. L. M., Van Gorp, T., de Kroon, C. D., van Lonkhuijzen, L. R. C. W., Massuger, L. F. A. G., Smolders, R. G. V., van Trommel, N. E., Yigit, R., Zweemer, R. P. & van der Aa, M. A., Jul-2020, In : Acta Obstetricia et Gynecologica Scandinavica. 99, 7, p. 925-932 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Wenzel, H. H. B., Kruitwagen, R. F. P. M., Nijman, H. W., Bekkers, R. L. M., Van Gorp, T., de Kroon, C. D., van Lonkhuijzen, L. R. C. W., Massuger, L. F. A. G., Smolders, R. G. V., van Trommel, N. E., Yigit, R., Zweemer, R. P., & van der Aa, M. A. (2020). Short-term surgical complications after radical hysterectomy - a nationwide cohort study. Acta Obstetricia et Gynecologica Scandinavica, 99(7), 925-932. https://doi.org/10.1111/aogs.13812

Author

Wenzel, Hans H B ; Kruitwagen, Roy F P M ; Nijman, Hans W ; Bekkers, Ruud L M ; Van Gorp, Toon ; de Kroon, Cornelis D ; van Lonkhuijzen, Luc R C W ; Massuger, Leon F A G ; Smolders, Ramon G V ; van Trommel, Nienke E ; Yigit, Refika ; Zweemer, Ronald P ; van der Aa, Maaike A. / Short-term surgical complications after radical hysterectomy - a nationwide cohort study. In: Acta Obstetricia et Gynecologica Scandinavica. 2020 ; Vol. 99, No. 7. pp. 925-932.

Harvard

Wenzel, HHB, Kruitwagen, RFPM, Nijman, HW, Bekkers, RLM, Van Gorp, T, de Kroon, CD, van Lonkhuijzen, LRCW, Massuger, LFAG, Smolders, RGV, van Trommel, NE, Yigit, R, Zweemer, RP & van der Aa, MA 2020, 'Short-term surgical complications after radical hysterectomy - a nationwide cohort study', Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 7, pp. 925-932. https://doi.org/10.1111/aogs.13812

Standard

Short-term surgical complications after radical hysterectomy - a nationwide cohort study. / Wenzel, Hans H B; Kruitwagen, Roy F P M; Nijman, Hans W; Bekkers, Ruud L M; Van Gorp, Toon; de Kroon, Cornelis D; van Lonkhuijzen, Luc R C W; Massuger, Leon F A G; Smolders, Ramon G V; van Trommel, Nienke E; Yigit, Refika; Zweemer, Ronald P; van der Aa, Maaike A.

In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 99, No. 7, 07.2020, p. 925-932.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Wenzel HHB, Kruitwagen RFPM, Nijman HW, Bekkers RLM, Van Gorp T, de Kroon CD et al. Short-term surgical complications after radical hysterectomy - a nationwide cohort study. Acta Obstetricia et Gynecologica Scandinavica. 2020 Jul;99(7):925-932. https://doi.org/10.1111/aogs.13812


BibTeX

@article{c1bfe58e06cc4a6e8ffab03815311137,
title = "Short-term surgical complications after radical hysterectomy - a nationwide cohort study",
abstract = "INTRODUCTION: Centralisation has, among other aspects, been argued to have an impact on quality of care in terms of surgical morbidity. Next, monitoring quality of care is essential in identifying areas of improvement. This nationwide cohort study was conducted to determine the rate of short-term surgical complications and to evaluate its possible predictors in women with early-stage cervical cancer.MATERIAL AND METHODS: Women diagnosed with early-stage cervical cancer, 2009 FIGO stages IB1 and IIA1, between 2015 and 2017 who underwent radical hysterectomy with pelvic lymphadenectomy in one of the nine specialised medical centres in the Netherlands, were identified from the Netherlands Cancer Registry. Women were excluded if primary treatment consisted of hysterectomy without parametrial dissection or radical trachelectomy. Women of whom radical hysterectomy has been aborted during procedure, were also excluded. Occurrence of intraoperative and postoperative complications and type of complications, developing within 30 days after surgery, were prospectively registered. Multivariable logistic regression analysis was used to identify predictors of surgical complications.RESULTS: 472 women were selected of which 166 (35%) developed surgical complications within 30 days after radical hysterectomy. The most frequent complications were urinary retention with catheterisation in 73 women (15%) and excessive perioperative blood loss > 1000 mL in 50 women (11%). Open surgery (Odds Ratio (OR) 3.42; 95% CI [1.73 to 6.76]), chronic pulmonary disease (OR 3.14; [1.45 to 6.79]), vascular disease (OR 1.90; [1.07 to 3.38]) and medical centre (OR 2.83; [1.18 to 6.77]) emerged as independent predictors of the occurrence of complications. Body mass index (OR 0.94; [0.89 to 1.00]) was found as a negative predictor of urinary retention. Open surgery (OR 36.65; [7.10 to 189.12]) and body mass index (OR 1.15; [1.08 to 1.22]) were found to be independent predictors of excessive perioperative blood loss.CONCLUSIONS: Short-term surgical complications develop in 35% of the women after radical hysterectomy for early-stage cervical cancer in the Netherlands, a nation with centralised surgical care. Comorbidities predict surgical complications and open surgery is associated with excessive perioperative blood loss.",
author = "Wenzel, {Hans H B} and Kruitwagen, {Roy F P M} and Nijman, {Hans W} and Bekkers, {Ruud L M} and {Van Gorp}, Toon and {de Kroon}, {Cornelis D} and {van Lonkhuijzen}, {Luc R C W} and Massuger, {Leon F A G} and Smolders, {Ramon G V} and {van Trommel}, {Nienke E} and Refika Yigit and Zweemer, {Ronald P} and {van der Aa}, {Maaike A}",
note = "{\textcopyright} 2020 Nordic Federation of Societies of Obstetrics and Gynecology.",
year = "2020",
month = jul,
doi = "10.1111/aogs.13812",
language = "English",
volume = "99",
pages = "925--932",
journal = "Acta Obstetricia et Gynecologica Scandinavica",
issn = "0001-6349",
publisher = "Wiley",
number = "7",

}

RIS

TY - JOUR

T1 - Short-term surgical complications after radical hysterectomy - a nationwide cohort study

AU - Wenzel, Hans H B

AU - Kruitwagen, Roy F P M

AU - Nijman, Hans W

AU - Bekkers, Ruud L M

AU - Van Gorp, Toon

AU - de Kroon, Cornelis D

AU - van Lonkhuijzen, Luc R C W

AU - Massuger, Leon F A G

AU - Smolders, Ramon G V

AU - van Trommel, Nienke E

AU - Yigit, Refika

AU - Zweemer, Ronald P

AU - van der Aa, Maaike A

N1 - © 2020 Nordic Federation of Societies of Obstetrics and Gynecology.

PY - 2020/7

Y1 - 2020/7

N2 - INTRODUCTION: Centralisation has, among other aspects, been argued to have an impact on quality of care in terms of surgical morbidity. Next, monitoring quality of care is essential in identifying areas of improvement. This nationwide cohort study was conducted to determine the rate of short-term surgical complications and to evaluate its possible predictors in women with early-stage cervical cancer.MATERIAL AND METHODS: Women diagnosed with early-stage cervical cancer, 2009 FIGO stages IB1 and IIA1, between 2015 and 2017 who underwent radical hysterectomy with pelvic lymphadenectomy in one of the nine specialised medical centres in the Netherlands, were identified from the Netherlands Cancer Registry. Women were excluded if primary treatment consisted of hysterectomy without parametrial dissection or radical trachelectomy. Women of whom radical hysterectomy has been aborted during procedure, were also excluded. Occurrence of intraoperative and postoperative complications and type of complications, developing within 30 days after surgery, were prospectively registered. Multivariable logistic regression analysis was used to identify predictors of surgical complications.RESULTS: 472 women were selected of which 166 (35%) developed surgical complications within 30 days after radical hysterectomy. The most frequent complications were urinary retention with catheterisation in 73 women (15%) and excessive perioperative blood loss > 1000 mL in 50 women (11%). Open surgery (Odds Ratio (OR) 3.42; 95% CI [1.73 to 6.76]), chronic pulmonary disease (OR 3.14; [1.45 to 6.79]), vascular disease (OR 1.90; [1.07 to 3.38]) and medical centre (OR 2.83; [1.18 to 6.77]) emerged as independent predictors of the occurrence of complications. Body mass index (OR 0.94; [0.89 to 1.00]) was found as a negative predictor of urinary retention. Open surgery (OR 36.65; [7.10 to 189.12]) and body mass index (OR 1.15; [1.08 to 1.22]) were found to be independent predictors of excessive perioperative blood loss.CONCLUSIONS: Short-term surgical complications develop in 35% of the women after radical hysterectomy for early-stage cervical cancer in the Netherlands, a nation with centralised surgical care. Comorbidities predict surgical complications and open surgery is associated with excessive perioperative blood loss.

AB - INTRODUCTION: Centralisation has, among other aspects, been argued to have an impact on quality of care in terms of surgical morbidity. Next, monitoring quality of care is essential in identifying areas of improvement. This nationwide cohort study was conducted to determine the rate of short-term surgical complications and to evaluate its possible predictors in women with early-stage cervical cancer.MATERIAL AND METHODS: Women diagnosed with early-stage cervical cancer, 2009 FIGO stages IB1 and IIA1, between 2015 and 2017 who underwent radical hysterectomy with pelvic lymphadenectomy in one of the nine specialised medical centres in the Netherlands, were identified from the Netherlands Cancer Registry. Women were excluded if primary treatment consisted of hysterectomy without parametrial dissection or radical trachelectomy. Women of whom radical hysterectomy has been aborted during procedure, were also excluded. Occurrence of intraoperative and postoperative complications and type of complications, developing within 30 days after surgery, were prospectively registered. Multivariable logistic regression analysis was used to identify predictors of surgical complications.RESULTS: 472 women were selected of which 166 (35%) developed surgical complications within 30 days after radical hysterectomy. The most frequent complications were urinary retention with catheterisation in 73 women (15%) and excessive perioperative blood loss > 1000 mL in 50 women (11%). Open surgery (Odds Ratio (OR) 3.42; 95% CI [1.73 to 6.76]), chronic pulmonary disease (OR 3.14; [1.45 to 6.79]), vascular disease (OR 1.90; [1.07 to 3.38]) and medical centre (OR 2.83; [1.18 to 6.77]) emerged as independent predictors of the occurrence of complications. Body mass index (OR 0.94; [0.89 to 1.00]) was found as a negative predictor of urinary retention. Open surgery (OR 36.65; [7.10 to 189.12]) and body mass index (OR 1.15; [1.08 to 1.22]) were found to be independent predictors of excessive perioperative blood loss.CONCLUSIONS: Short-term surgical complications develop in 35% of the women after radical hysterectomy for early-stage cervical cancer in the Netherlands, a nation with centralised surgical care. Comorbidities predict surgical complications and open surgery is associated with excessive perioperative blood loss.

U2 - 10.1111/aogs.13812

DO - 10.1111/aogs.13812

M3 - Article

C2 - 31955408

VL - 99

SP - 925

EP - 932

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

SN - 0001-6349

IS - 7

ER -

ID: 113433872