TY - JOUR

T1 - Severe periodontitis is more common in HIV- infected patients

AU - Groenewegen, Hester

AU - Bierman, Wouter F W

AU - Delli, Konstantina

AU - Dijkstra, Pieter U

AU - Nesse, Willem

AU - Vissink, Arjan

AU - Spijkervet, Frederik K L

N1 - Copyright © 2018. Published by Elsevier Ltd.

PY - 2019/3

Y1 - 2019/3

N2 - Objective: To assess periodontitis prevalence and severity in HIV infected patients as compared to controls. Furthermore, to assess whether HIV infection characteristics are associated with periodontitis.Design: cross-sectional controlled study.Methods: We assessed prevalence and severity of periodontitis in 258 HIV-infected patients and 539 historical controls with the Dutch Periodontal Screening Index (DPSI). HIV characteristics were collected from medical charts. Age-related diseases and oral care were assessed with questionnaires.Results: Severe periodontitis (DPSI 4) was more prevalent in HIV-infected patients than in controls (66% vs. 36%, p =0.002). HIV-infection, increasing age and male sex were significant risk factors for severe periodontitis. In particular, older male HIV patients have a higher risk of severe periodontitis. Clinical, immunological and virologic characteristics, and antiretroviral therapy were not associated with periodontitis prevalence or severity. HIV-infected patients rate the importance of their oral health as high, although many do not disclose their HIV infection to their dentists.Conclusions: Prevalence and severity of periodontitis are higher in HIV-infected patients compared to controls, particularly in older males. Awareness of the increased prevalence of periodontitis associated with HIV-infection among patients and health-care professionals could significantly improve oral health and quality of life of HIV-infected patients. (C) 2018 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

AB - Objective: To assess periodontitis prevalence and severity in HIV infected patients as compared to controls. Furthermore, to assess whether HIV infection characteristics are associated with periodontitis.Design: cross-sectional controlled study.Methods: We assessed prevalence and severity of periodontitis in 258 HIV-infected patients and 539 historical controls with the Dutch Periodontal Screening Index (DPSI). HIV characteristics were collected from medical charts. Age-related diseases and oral care were assessed with questionnaires.Results: Severe periodontitis (DPSI 4) was more prevalent in HIV-infected patients than in controls (66% vs. 36%, p =0.002). HIV-infection, increasing age and male sex were significant risk factors for severe periodontitis. In particular, older male HIV patients have a higher risk of severe periodontitis. Clinical, immunological and virologic characteristics, and antiretroviral therapy were not associated with periodontitis prevalence or severity. HIV-infected patients rate the importance of their oral health as high, although many do not disclose their HIV infection to their dentists.Conclusions: Prevalence and severity of periodontitis are higher in HIV-infected patients compared to controls, particularly in older males. Awareness of the increased prevalence of periodontitis associated with HIV-infection among patients and health-care professionals could significantly improve oral health and quality of life of HIV-infected patients. (C) 2018 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

KW - HIV infection

KW - Periodontitis

KW - Prevalence

KW - ORAL LESIONS

KW - ANTIRETROVIRAL THERAPY

KW - POSITIVE PATIENTS

KW - RISK-FACTORS

KW - PREVALENCE

KW - DISEASE

KW - SMOKING

KW - ADULTS

KW - CLASSIFICATION

KW - INFLAMMATION

U2 - 10.1016/j.jinf.2018.11.008

DO - 10.1016/j.jinf.2018.11.008

M3 - Article

C2 - 30528870

VL - 78

SP - 171

EP - 177

JO - Journal of infection

JF - Journal of infection

SN - 0163-4453

IS - 3

ER -