Publication

Science Forum: The Human Cell Atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P. J., Carninci, P., Clatworthy, M., Clevers, H., Deplancke, B., Dunham, I., Eberwine, J., Eils, R., Enard, W., Farmer, A., Fugger, L., Göttgens, B., Hacohen, N., Haniffa, M., Hemberg, M., Kim, S. K., Klenerman, P., Kriegstein, A., Lein, E., Linnarsson, S., Lundberg, E., Lundeberg, J., Majumder, P., Marioni, J. C., Merad, M., Mhlanga, M., Nawijn, M., Netea, M., Nolan, G., Pe'er, D., Phillipakis, A., Ponting, C. P., Quake, S. R., Reik, W., Rozenblatt-Rosen, O., Sanes, J. R., Satija, R., Schumacher, T. N., Shalek, A. K., Shapiro, E., Sharma, P., Shin, J. W., Stegle, O. & Human Cell Atlas Meeting Participants, 5-Dec-2017, In : eLife. 6, e27041.

Research output: Contribution to journalArticleAcademicpeer-review

Copy link to clipboard

Documents

DOI

  • Aviv Regev
  • Sarah A Teichmann
  • Eric S Lander
  • Ido Amit
  • Christophe Benoist
  • Ewan Birney
  • Bernd Bodenmiller
  • Peter J Campbell
  • Piero Carninci
  • Menna Clatworthy
  • Hans Clevers
  • Bart Deplancke
  • Ian Dunham
  • James Eberwine
  • Roland Eils
  • Wolfgang Enard
  • Andrew Farmer
  • Lars Fugger
  • Berthold Göttgens
  • Nir Hacohen
  • Muzlifah Haniffa
  • Martin Hemberg
  • Seung K Kim
  • Paul Klenerman
  • Arnold Kriegstein
  • Ed Lein
  • Sten Linnarsson
  • Emma Lundberg
  • Joakim Lundeberg
  • Partha Majumder
  • John C Marioni
  • Miriam Merad
  • Musa Mhlanga
  • Martijn Nawijn
  • Mihai Netea
  • Garry Nolan
  • Dana Pe'er
  • Anthony Phillipakis
  • Chris P Ponting
  • Stephen R Quake
  • Wolf Reik
  • Orit Rozenblatt-Rosen
  • Joshua R Sanes
  • Rahul Satija
  • Ton N Schumacher
  • Alex K Shalek
  • Ehud Shapiro
  • Padmanee Sharma
  • Jay W Shin
  • Oliver Stegle
  • Human Cell Atlas Meeting Participants

The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology). An open comprehensive reference map of the molecular state of cells in healthy human tissues would propel the systematic study of physiological states, developmental trajectories, regulatory circuitry and interactions of cells, and also provide a framework for understanding cellular dysregulation in human disease. Here we describe the idea, its potential utility, early proofs-of-concept, and some design considerations for the Human Cell Atlas, including a commitment to open data, code, and community.

Original languageEnglish
Article numbere27041
JournaleLife
Volume6
Publication statusPublished - 5-Dec-2017

    Keywords

  • Journal Article, CHROMATIN ACCESSIBILITY, HEMATOPOIETIC STEM, EMBRYONIC STEM-CELLS, WADDINGTONS EPIGENETIC LANDSCAPE, HUMAN BRAIN TRANSCRIPTOME, IN-SITU HYBRIDIZATION, RNA-SEQ DATA, GENE-EXPRESSION, SINGLE CELLS, MESSENGER-RNA

Download statistics

No data available

ID: 51334639