Publication

Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)

Noorduin, W. L., Asdonk, P. V. D., Bode, A. A. C., Meekes, H., Enckevort, W. J. P. V., Vlieg, E., Kaptein, B., Meijden, M. W. V. D., Kellogg, R. M. & Deroover, G., 2010, In : Organic Process Research & Development. 14, 4, p. 908-911 4 p.

Research output: Contribution to journalArticleAcademic

APA

Noorduin, W. L., Asdonk, P. V. D., Bode, A. A. C., Meekes, H., Enckevort, W. J. P. V., Vlieg, E., Kaptein, B., Meijden, M. W. V. D., Kellogg, R. M., & Deroover, G. (2010). Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). Organic Process Research & Development, 14(4), 908-911. https://doi.org/10.1021/op1001116

Author

Noorduin, W.L. ; Asdonk, P. van der ; Bode, A.A.C. ; Meekes, H. ; Enckevort, W.J.P. van ; Vlieg, E. ; Kaptein, B. ; Meijden, M.W. van der ; Kellogg, R.M. ; Deroover, G. / Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). In: Organic Process Research & Development. 2010 ; Vol. 14, No. 4. pp. 908-911.

Harvard

Noorduin, WL, Asdonk, PVD, Bode, AAC, Meekes, H, Enckevort, WJPV, Vlieg, E, Kaptein, B, Meijden, MWVD, Kellogg, RM & Deroover, G 2010, 'Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)', Organic Process Research & Development, vol. 14, no. 4, pp. 908-911. https://doi.org/10.1021/op1001116

Standard

Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). / Noorduin, W.L.; Asdonk, P. van der; Bode, A.A.C.; Meekes, H.; Enckevort, W.J.P. van; Vlieg, E.; Kaptein, B.; Meijden, M.W. van der; Kellogg, R.M.; Deroover, G.

In: Organic Process Research & Development, Vol. 14, No. 4, 2010, p. 908-911.

Research output: Contribution to journalArticleAcademic

Vancouver

Noorduin WL, Asdonk PVD, Bode AAC, Meekes H, Enckevort WJPV, Vlieg E et al. Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). Organic Process Research & Development. 2010;14(4):908-911. https://doi.org/10.1021/op1001116


BibTeX

@article{11ed28f0d5194ecc91d732ddb1195654,
title = "Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)",
abstract = "The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.",
author = "W.L. Noorduin and Asdonk, {P. van der} and A.A.C. Bode and H. Meekes and Enckevort, {W.J.P. van} and E. Vlieg and B. Kaptein and Meijden, {M.W. van der} and R.M. Kellogg and G. Deroover",
note = "Relation: https://www.rug.nl/scheikunde/onderzoek/scholen/stratingh/index date_submitted:2011 Rights: University of Groningen, Stratingh Institute for Chemistry",
year = "2010",
doi = "10.1021/op1001116",
language = "English",
volume = "14",
pages = "908--911",
journal = "Organic Process Research and Development",
issn = "1083-6160",
publisher = "AMER CHEMICAL SOC INC",
number = "4",

}

RIS

TY - JOUR

T1 - Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)

AU - Noorduin, W.L.

AU - Asdonk, P. van der

AU - Bode, A.A.C.

AU - Meekes, H.

AU - Enckevort, W.J.P. van

AU - Vlieg, E.

AU - Kaptein, B.

AU - Meijden, M.W. van der

AU - Kellogg, R.M.

AU - Deroover, G.

N1 - Relation: https://www.rug.nl/scheikunde/onderzoek/scholen/stratingh/index date_submitted:2011 Rights: University of Groningen, Stratingh Institute for Chemistry

PY - 2010

Y1 - 2010

N2 - The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.

AB - The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.

U2 - 10.1021/op1001116

DO - 10.1021/op1001116

M3 - Article

VL - 14

SP - 908

EP - 911

JO - Organic Process Research and Development

JF - Organic Process Research and Development

SN - 1083-6160

IS - 4

ER -

ID: 2630806