Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)
Noorduin, W. L., Asdonk, P. V. D., Bode, A. A. C., Meekes, H., Enckevort, W. J. P. V., Vlieg, E., Kaptein, B., Meijden, M. W. V. D., Kellogg, R. M. & Deroover, G.,
2010,
In : Organic Process Research & Development. 14,
4,
p. 908-911 4 p.Research output: Contribution to journal › Article › Academic
APA
Noorduin, W. L., Asdonk, P. V. D., Bode, A. A. C., Meekes, H., Enckevort, W. J. P. V., Vlieg, E., Kaptein, B., Meijden, M. W. V. D., Kellogg, R. M., & Deroover, G. (2010).
Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix).
Organic Process Research & Development,
14(4), 908-911.
https://doi.org/10.1021/op1001116Author
Noorduin, W.L. ; Asdonk, P. van der ; Bode, A.A.C. ; Meekes, H. ; Enckevort, W.J.P. van ; Vlieg, E. ; Kaptein, B. ; Meijden, M.W. van der ; Kellogg, R.M. ; Deroover, G. / Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). In: Organic Process Research & Development. 2010 ; Vol. 14, No. 4. pp. 908-911.
Harvard
Noorduin, WL, Asdonk, PVD, Bode, AAC, Meekes, H, Enckevort, WJPV, Vlieg, E, Kaptein, B, Meijden, MWVD, Kellogg, RM & Deroover, G 2010, '
Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)',
Organic Process Research & Development, vol. 14, no. 4, pp. 908-911.
https://doi.org/10.1021/op1001116Standard
Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix). / Noorduin, W.L.; Asdonk, P. van der; Bode, A.A.C.; Meekes, H.; Enckevort, W.J.P. van; Vlieg, E.; Kaptein, B.; Meijden, M.W. van der; Kellogg, R.M.; Deroover, G.
In:
Organic Process Research & Development, Vol. 14, No. 4, 2010, p. 908-911.
Research output: Contribution to journal › Article › Academic
Vancouver
Noorduin WL, Asdonk PVD, Bode AAC, Meekes H, Enckevort WJPV, Vlieg E et al.
Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix).
Organic Process Research & Development. 2010;14(4):908-911.
https://doi.org/10.1021/op1001116
BibTeX
@article{11ed28f0d5194ecc91d732ddb1195654,
title = "Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)",
abstract = "The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.",
author = "W.L. Noorduin and Asdonk, {P. van der} and A.A.C. Bode and H. Meekes and Enckevort, {W.J.P. van} and E. Vlieg and B. Kaptein and Meijden, {M.W. van der} and R.M. Kellogg and G. Deroover",
note = "Relation: https://www.rug.nl/scheikunde/onderzoek/scholen/stratingh/index date_submitted:2011 Rights: University of Groningen, Stratingh Institute for Chemistry",
year = "2010",
doi = "10.1021/op1001116",
language = "English",
volume = "14",
pages = "908--911",
journal = "Organic Process Research and Development",
issn = "1083-6160",
publisher = "AMER CHEMICAL SOC INC",
number = "4",
}
RIS
TY - JOUR
T1 - Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)
AU - Noorduin, W.L.
AU - Asdonk, P. van der
AU - Bode, A.A.C.
AU - Meekes, H.
AU - Enckevort, W.J.P. van
AU - Vlieg, E.
AU - Kaptein, B.
AU - Meijden, M.W. van der
AU - Kellogg, R.M.
AU - Deroover, G.
N1 - Relation: https://www.rug.nl/scheikunde/onderzoek/scholen/stratingh/index
date_submitted:2011
Rights: University of Groningen, Stratingh Institute for Chemistry
PY - 2010
Y1 - 2010
N2 - The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.
AB - The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is drastically reduced as a result of the efficient grinding that can be achieved using bead mills.
U2 - 10.1021/op1001116
DO - 10.1021/op1001116
M3 - Article
VL - 14
SP - 908
EP - 911
JO - Organic Process Research and Development
JF - Organic Process Research and Development
SN - 1083-6160
IS - 4
ER -
