Publication

Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease

Bravo-Sagua, R., Parra, V., Muñoz-Cordova, F., Sanchez-Aguilera, P., Garrido, V., Contreras-Ferrat, A., Chiong, M. & Lavandero, S., 2020, International Review of Cell and Molecular Biology. Elsevier, Vol. 350. p. 197-264 68 p. (International Journal of Cell Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

APA

Bravo-Sagua, R., Parra, V., Muñoz-Cordova, F., Sanchez-Aguilera, P., Garrido, V., Contreras-Ferrat, A., Chiong, M., & Lavandero, S. (2020). Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease. In International Review of Cell and Molecular Biology (Vol. 350, pp. 197-264). (International Journal of Cell Biology). Elsevier. https://doi.org/10.1016/bs.ircmb.2019.12.007

Author

Bravo-Sagua, Roberto ; Parra, Valentina ; Muñoz-Cordova, Felipe ; Sanchez-Aguilera, Pablo ; Garrido, Valeria ; Contreras-Ferrat, Ariel ; Chiong, Mario ; Lavandero, Sergio. / Sarcoplasmic reticulum and calcium signaling in muscle cells : Homeostasis and disease. International Review of Cell and Molecular Biology. Vol. 350 Elsevier, 2020. pp. 197-264 (International Journal of Cell Biology).

Harvard

Bravo-Sagua, R, Parra, V, Muñoz-Cordova, F, Sanchez-Aguilera, P, Garrido, V, Contreras-Ferrat, A, Chiong, M & Lavandero, S 2020, Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease. in International Review of Cell and Molecular Biology. vol. 350, International Journal of Cell Biology, Elsevier, pp. 197-264. https://doi.org/10.1016/bs.ircmb.2019.12.007

Standard

Sarcoplasmic reticulum and calcium signaling in muscle cells : Homeostasis and disease. / Bravo-Sagua, Roberto; Parra, Valentina; Muñoz-Cordova, Felipe; Sanchez-Aguilera, Pablo; Garrido, Valeria; Contreras-Ferrat, Ariel; Chiong, Mario; Lavandero, Sergio.

International Review of Cell and Molecular Biology. Vol. 350 Elsevier, 2020. p. 197-264 (International Journal of Cell Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Vancouver

Bravo-Sagua R, Parra V, Muñoz-Cordova F, Sanchez-Aguilera P, Garrido V, Contreras-Ferrat A et al. Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease. In International Review of Cell and Molecular Biology. Vol. 350. Elsevier. 2020. p. 197-264. (International Journal of Cell Biology). https://doi.org/10.1016/bs.ircmb.2019.12.007


BibTeX

@inbook{4f13150de366498c982417dbc42a7a55,
title = "Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease",
abstract = "The sarco/endoplasmic reticulum is an extensive, dynamic and heterogeneous membranous network that fulfills multiple homeostatic functions. Among them, it compartmentalizes, stores and releases calcium within the intracellular space. In the case of muscle cells, calcium released from the sarco/endoplasmic reticulum in the vicinity of the contractile machinery induces cell contraction. Furthermore, sarco/endoplasmic reticulum-derived calcium also regulates gene transcription in the nucleus, energy metabolism in mitochondria and cytosolic signaling pathways. These diverse and overlapping processes require a highly complex fine-tuning that the sarco/endoplasmic reticulum provides by means of its numerous tubules and cisternae, specialized domains and contacts with other organelles. The sarco/endoplasmic reticulum also possesses a rich calcium-handling machinery, functionally coupled to both contraction-inducing stimuli and the contractile apparatus. Such is the importance of the sarco/endoplasmic reticulum for muscle cell physiology, that alterations in its structure, function or its calcium-handling machinery are intimately associated with the development of cardiometabolic diseases. Cardiac hypertrophy, insulin resistance and arterial hypertension are age-related pathologies with a common mechanism at the muscle cell level: the accumulation of damaged proteins at the sarco/endoplasmic reticulum induces a stress response condition termed endoplasmic reticulum stress, which impairs proper organelle function, ultimately leading to pathogenesis.",
author = "Roberto Bravo-Sagua and Valentina Parra and Felipe Mu{\~n}oz-Cordova and Pablo Sanchez-Aguilera and Valeria Garrido and Ariel Contreras-Ferrat and Mario Chiong and Sergio Lavandero",
note = "{\textcopyright} 2020 Elsevier Inc. All rights reserved.",
year = "2020",
doi = "10.1016/bs.ircmb.2019.12.007",
language = "English",
volume = "350",
series = "International Journal of Cell Biology",
publisher = "Elsevier",
pages = "197--264",
booktitle = "International Review of Cell and Molecular Biology",

}

RIS

TY - CHAP

T1 - Sarcoplasmic reticulum and calcium signaling in muscle cells

T2 - Homeostasis and disease

AU - Bravo-Sagua, Roberto

AU - Parra, Valentina

AU - Muñoz-Cordova, Felipe

AU - Sanchez-Aguilera, Pablo

AU - Garrido, Valeria

AU - Contreras-Ferrat, Ariel

AU - Chiong, Mario

AU - Lavandero, Sergio

N1 - © 2020 Elsevier Inc. All rights reserved.

PY - 2020

Y1 - 2020

N2 - The sarco/endoplasmic reticulum is an extensive, dynamic and heterogeneous membranous network that fulfills multiple homeostatic functions. Among them, it compartmentalizes, stores and releases calcium within the intracellular space. In the case of muscle cells, calcium released from the sarco/endoplasmic reticulum in the vicinity of the contractile machinery induces cell contraction. Furthermore, sarco/endoplasmic reticulum-derived calcium also regulates gene transcription in the nucleus, energy metabolism in mitochondria and cytosolic signaling pathways. These diverse and overlapping processes require a highly complex fine-tuning that the sarco/endoplasmic reticulum provides by means of its numerous tubules and cisternae, specialized domains and contacts with other organelles. The sarco/endoplasmic reticulum also possesses a rich calcium-handling machinery, functionally coupled to both contraction-inducing stimuli and the contractile apparatus. Such is the importance of the sarco/endoplasmic reticulum for muscle cell physiology, that alterations in its structure, function or its calcium-handling machinery are intimately associated with the development of cardiometabolic diseases. Cardiac hypertrophy, insulin resistance and arterial hypertension are age-related pathologies with a common mechanism at the muscle cell level: the accumulation of damaged proteins at the sarco/endoplasmic reticulum induces a stress response condition termed endoplasmic reticulum stress, which impairs proper organelle function, ultimately leading to pathogenesis.

AB - The sarco/endoplasmic reticulum is an extensive, dynamic and heterogeneous membranous network that fulfills multiple homeostatic functions. Among them, it compartmentalizes, stores and releases calcium within the intracellular space. In the case of muscle cells, calcium released from the sarco/endoplasmic reticulum in the vicinity of the contractile machinery induces cell contraction. Furthermore, sarco/endoplasmic reticulum-derived calcium also regulates gene transcription in the nucleus, energy metabolism in mitochondria and cytosolic signaling pathways. These diverse and overlapping processes require a highly complex fine-tuning that the sarco/endoplasmic reticulum provides by means of its numerous tubules and cisternae, specialized domains and contacts with other organelles. The sarco/endoplasmic reticulum also possesses a rich calcium-handling machinery, functionally coupled to both contraction-inducing stimuli and the contractile apparatus. Such is the importance of the sarco/endoplasmic reticulum for muscle cell physiology, that alterations in its structure, function or its calcium-handling machinery are intimately associated with the development of cardiometabolic diseases. Cardiac hypertrophy, insulin resistance and arterial hypertension are age-related pathologies with a common mechanism at the muscle cell level: the accumulation of damaged proteins at the sarco/endoplasmic reticulum induces a stress response condition termed endoplasmic reticulum stress, which impairs proper organelle function, ultimately leading to pathogenesis.

U2 - 10.1016/bs.ircmb.2019.12.007

DO - 10.1016/bs.ircmb.2019.12.007

M3 - Chapter

C2 - 32138900

VL - 350

T3 - International Journal of Cell Biology

SP - 197

EP - 264

BT - International Review of Cell and Molecular Biology

PB - Elsevier

ER -

ID: 128948138