Publication

Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris

De Muinck, E. D. & Lie, K. I., 1990, In : Journal of Cardiovascular Pharmacology. 16, p. S123-S128 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

De Muinck, E. D., & Lie, K. I. (1990). Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris. Journal of Cardiovascular Pharmacology, 16, S123-S128.

Author

De Muinck, E. D. ; Lie, K. I. / Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris. In: Journal of Cardiovascular Pharmacology. 1990 ; Vol. 16. pp. S123-S128.

Harvard

De Muinck, ED & Lie, KI 1990, 'Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris', Journal of Cardiovascular Pharmacology, vol. 16, pp. S123-S128.

Standard

Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris. / De Muinck, E. D.; Lie, K. I.

In: Journal of Cardiovascular Pharmacology, Vol. 16, 1990, p. S123-S128.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

De Muinck ED, Lie KI. Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris. Journal of Cardiovascular Pharmacology. 1990;16:S123-S128.


BibTeX

@article{70b1bae94d3f4ba8afac8f688795b5e9,
title = "Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris",
abstract = "In stable exercise-induced angina pectoris, beta-blockers exert their beneficial effects mainly through a reduction in heart rate, blood pressure, and contractility. Additional beneficial effects are an improvement in myocardial oxygen supply through a redistribution of coronary flow, a lengthening of diastole, a facilitation of aerobic metabolism, and a rightward shift of the oxygen-hemoglobin dissociation curve. Cardioselective beta-blockers can be expected to have fewer side effects than the nonselective drugs. Apart from a reduction in anginal attack rate and an improvement in exercise capacity, a reduction in silent ischemia may be desirable when treating patients with stable effort angina. Beta-blockers effectively reduce asymptomatic ischemia. Bisorprolol is a new beta-1-selective beta-blocker with a clear 24-h duration of action regarding symptoms stable exercise-induced angina pectoris. Bisoprolol 10 mg and atenolol 100 mg are equipotent in achieving these effects.",
keywords = "BETA-BLOCKADE, EFFORT ANGINA, OVERVIEW, INTRINSIC SYMPATHOMIMETIC ACTIVITY, SILENT MYOCARDIAL ISCHEMIA, CORONARY-ARTERY DISEASE, EXERCISE TOLERANCE, HEART-DISEASE, PROPRANOLOL, PINDOLOL, ATENOLOL, BLOCKADE, DRUGS",
author = "{De Muinck}, {E. D.} and Lie, {K. I.}",
year = "1990",
language = "English",
volume = "16",
pages = "S123--S128",
journal = "Journal of Cardiovascular Pharmacology",
issn = "0160-2446",
note = "3RD INTERNATIONAL SYMP ON BISOPROLOL : THE ROLE OF BETA-BLOCKADE IN MODERN CARDIOVASCULAR THERAPY ; Conference date: 29-09-1989 Through 01-10-1989",

}

RIS

TY - JOUR

T1 - Safety and Efficacy of Beta-Blockers in the Treatment of Stable Angina Pectoris

AU - De Muinck, E. D.

AU - Lie, K. I.

PY - 1990

Y1 - 1990

N2 - In stable exercise-induced angina pectoris, beta-blockers exert their beneficial effects mainly through a reduction in heart rate, blood pressure, and contractility. Additional beneficial effects are an improvement in myocardial oxygen supply through a redistribution of coronary flow, a lengthening of diastole, a facilitation of aerobic metabolism, and a rightward shift of the oxygen-hemoglobin dissociation curve. Cardioselective beta-blockers can be expected to have fewer side effects than the nonselective drugs. Apart from a reduction in anginal attack rate and an improvement in exercise capacity, a reduction in silent ischemia may be desirable when treating patients with stable effort angina. Beta-blockers effectively reduce asymptomatic ischemia. Bisorprolol is a new beta-1-selective beta-blocker with a clear 24-h duration of action regarding symptoms stable exercise-induced angina pectoris. Bisoprolol 10 mg and atenolol 100 mg are equipotent in achieving these effects.

AB - In stable exercise-induced angina pectoris, beta-blockers exert their beneficial effects mainly through a reduction in heart rate, blood pressure, and contractility. Additional beneficial effects are an improvement in myocardial oxygen supply through a redistribution of coronary flow, a lengthening of diastole, a facilitation of aerobic metabolism, and a rightward shift of the oxygen-hemoglobin dissociation curve. Cardioselective beta-blockers can be expected to have fewer side effects than the nonselective drugs. Apart from a reduction in anginal attack rate and an improvement in exercise capacity, a reduction in silent ischemia may be desirable when treating patients with stable effort angina. Beta-blockers effectively reduce asymptomatic ischemia. Bisorprolol is a new beta-1-selective beta-blocker with a clear 24-h duration of action regarding symptoms stable exercise-induced angina pectoris. Bisoprolol 10 mg and atenolol 100 mg are equipotent in achieving these effects.

KW - BETA-BLOCKADE

KW - EFFORT ANGINA

KW - OVERVIEW

KW - INTRINSIC SYMPATHOMIMETIC ACTIVITY

KW - SILENT MYOCARDIAL ISCHEMIA

KW - CORONARY-ARTERY DISEASE

KW - EXERCISE TOLERANCE

KW - HEART-DISEASE

KW - PROPRANOLOL

KW - PINDOLOL

KW - ATENOLOL

KW - BLOCKADE

KW - DRUGS

M3 - Article

VL - 16

SP - S123-S128

JO - Journal of Cardiovascular Pharmacology

JF - Journal of Cardiovascular Pharmacology

SN - 0160-2446

T2 - 3RD INTERNATIONAL SYMP ON BISOPROLOL : THE ROLE OF BETA-BLOCKADE IN MODERN CARDIOVASCULAR THERAPY

Y2 - 29 September 1989 through 1 October 1989

ER -

ID: 6278202