Risk factors for the transmission of methicillin-resistant Staphylococcus aureus in an adult intensive care unit: fitting a model to the dataGrundmann, H., Hori, S., Winter, B., Tami, A. & Austin, D. J., 15-Feb-2002, In : The Journal of Infectious Diseases. 185, 4, p. 481-488 8 p.
Research output: Contribution to journal › Article › Academic › peer-review
Little is known about the amount of cross-transmission, the risk factors for infection, and the relative effectiveness of infection control procedures when methicillin-resistant Staphylococcus aureus (MRSA) infection occurs at highly endemic levels in intensive care units. A cohort study was done to identify exposures associated with cases that likely were the result of cross-transmission (i.e., occurring in clusters and with indistinguishable MRSA macrorestriction profiles). Fitting a simple stochastic model to the ascertained data allowed prediction of the effectiveness of infection control measures. Exposure to relative staff deficit (adjusted rate ratio, 1.05 independent; 95% confidence interval, 1.02-1.09) was the only factor significantly associated with potential transmission (P =.001). It was predicted that a 12% improvement in adherence to hand-hygiene policies might have compensated for staff shortage and prevented transmission during periods of overcrowding, shared care, and high workload but that this would be hard to achieve.
|Number of pages||8|
|Journal||The Journal of Infectious Diseases|
|Publication status||Published - 15-Feb-2002|
- Cluster Analysis, Cross Infection/etiology, Humans, Intensive Care Units, Methicillin Resistance, Models, Biological, Risk Factors, Staphylococcal Infections/etiology, Staphylococcus aureus/drug effects