Retriever fetches integrins from endosomesRabouille, C., Oct-2017, In : Nature Cell Biology. 19, 10, p. 1144-1146 3 p.
Research output: Contribution to journal › Editorial › Academic › peer-review
Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α(5)β(1) integrins.
|Number of pages||3|
|Journal||Nature Cell Biology|
|Publication status||Published - Oct-2017|
- TRANS-GOLGI NETWORK, RETROGRADE TRANSPORT, RETROMER, COMPLEX, DEGRADATION, TRAFFICKING, RECOGNITION