Publication

Response time variability and response inhibition predict affective problems in adolescent girls, not in boys: the TRAILS study

van Deurzen, P. A. M., Buitelaar, J. K., Brunnekreef, J. A., Ormel, J., Minderaa, R. B., Hartman, C. A., Huizink, A. C., Speckens, A. E. M., Oldehinkel, A. J. & Slaats-Willemse, D. I. E., May-2012, In : European Child & Adolescent Psychiatry. 21, 5, p. 277-287 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The present study examines the relationship between neurocognitive functioning and affective problems through adolescence, in a cross-sectional and longitudinal perspective. Baseline response speed, response speed variability, response inhibition, attentional flexibility and working memory were assessed in a cohort of 2,179 adolescents (age 10-12 years) from the TRacking Adolescents' Individual Lives Survey (TRAILS). Affective problems were measured with the DSM-oriented Affective Problems scale of the Youth Self Report at wave 1 (baseline assessment), wave 2 (after 2.5 years) and wave 3 (after 5 years). Cross-sectionally, baseline response speed, response time variability, response inhibition and working memory were associated with baseline affective problems in girls, but not in boys. Longitudinally, enhanced response time variability predicted affective problems after 2.5 and 5 years in girls, but not in boys. Decreased response inhibition predicted affective problems after 5 years follow-up in girls, and again not in boys. The results are discussed in light of recent insights in gender differences in adolescence and state-trait issues in depression.

Original languageEnglish
Pages (from-to)277-287
Number of pages11
JournalEuropean Child & Adolescent Psychiatry
Volume21
Issue number5
Publication statusPublished - May-2012

    Keywords

  • Depression, Affective problems, Neuropsychology, Gender, Adolescence, Cohort, ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, EXTERNALIZING BEHAVIOR PROBLEMS, MAJOR DEPRESSIVE DISORDER, POPULATION-BASED SAMPLE, FOLLOW-UP, GENDER-DIFFERENCES, PREFRONTAL CORTEX, SEX-DIFFERENCES, DEVELOPMENTAL TRAJECTORIES, COGNITIVE PERFORMANCE

ID: 5560195