Rehabilitation of tendon problems in patients with diabetes mellitus

Rees, J., Gaida, J. E., Silbernagel, K. G., Zwerver, J., Anthony, J. S. & Scott, A., 2-Dec-2016, Metabolic Influences on Risk for Tendon Disorders . Ackermann, PW. & Hart, DA. (eds.). Springer New York LLC, Vol. 920. p. 199-208 10 p. (Advances in Experimental Medicine and Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

  • Jonathan Rees
  • Jamie E. Gaida
  • Karin Grävare Silbernagel
  • Johannes Zwerver
  • Joseph S. Anthony
  • Alex Scott
Exercise is crucial in the management of diabetes mellitus and its associated complications. However, individuals with diabetes have a heightened risk of musculoskeletal problems, including tendon pathologies. Diabetes has a significant impact on the function of tendons due to the accumulation of advanced glycation end-products in the load-bearing collagen. In addition, tendon vascularity and healing may be reduced due to diabetes-induced changes in the peripheral vascular system, and impaired synthesis of collagen and glycosaminoglycan. The current chapter presents an evidence-based discussion of considerations for the rehabilitation of tendon problems in people with diabetes. The following conditions are discussed in detail – calcific tendinopathy, tenosynovitis, tendon rupture, and non-calcifying tendinopathy. Common diabetes-related findings are presented, along with their potential impact on tendinopathy management and suggested modifications to standard tendinopathy treatment protocols. A holistic approach should be used to optimize musculotendinous function, including a comprehensive exercise prescription addressing strength, flexibility, and aerobic fitness.
Original languageEnglish
Title of host publicationMetabolic Influences on Risk for Tendon Disorders
EditorsPW Ackermann, DA Hart
PublisherSpringer New York LLC
Number of pages10
ISBN (Electronic)978-3-319-33943-6
ISBN (Print)978-3-319-33941-2
Publication statusPublished - 2-Dec-2016

Publication series

NameAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • Calcification, Diabetes, Rehabilitation, Rupture, Tendinopathy, Tendon, advanced glycation end product, collagen, glycosaminoglycan, autonomic neuropathy, body mass, calcific tendinopathy, cell aging, collagen synthesis, De Quervain tenosynovitis, decubitus, diabetes control, diabetes mellitus, Dupuytren contracture, exercise, glycemic control, glycosaminoglycan metabolism, grip strength, holistic care, human, humeroscapular periarthritis, hypercholesterolemia, hyperglycemia, hyperostosis, hypoglycemia, insulin dependent diabetes mellitus, insulin resistance, intermittent pneumatic compression device, muscle atrophy, musculoskeletal disease, neuropathic joint disease, non calcifying tendinopathy, non insulin dependent diabetes mellitus, orthopedic shoe, peripheral neuropathy, peripheral vascular disease, prevalence, priority journal, range of motion, rehabilitation, resistance training, rotator cuff, tendinitis, tendon disease, tendon rupture, tenosynovitis, weight reduction, wound healing impairment

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