Publication

Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors

Zheng, T., Martinez, F. P., Storm, I. M., Rombouts, W., Sprakel, J., Schirhagl, R. & de Vries, R., 5-Dec-2017, In : Analytical Chemistry. 89, 23, p. 12812-12820 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Zheng, T., Martinez, F. P., Storm, I. M., Rombouts, W., Sprakel, J., Schirhagl, R., & de Vries, R. (2017). Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors. Analytical Chemistry, 89(23), 12812-12820. https://doi.org/10.1021/acs.analchem.7b03236

Author

Zheng, Tingting ; Martinez, Felipe Perona ; Storm, Ingeborg Maria ; Rombouts, Wolf ; Sprakel, Joris ; Schirhagl, Romana ; de Vries, Renko. / Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors. In: Analytical Chemistry. 2017 ; Vol. 89, No. 23. pp. 12812-12820.

Harvard

Zheng, T, Martinez, FP, Storm, IM, Rombouts, W, Sprakel, J, Schirhagl, R & de Vries, R 2017, 'Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors', Analytical Chemistry, vol. 89, no. 23, pp. 12812-12820. https://doi.org/10.1021/acs.analchem.7b03236

Standard

Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors. / Zheng, Tingting; Martinez, Felipe Perona; Storm, Ingeborg Maria; Rombouts, Wolf; Sprakel, Joris; Schirhagl, Romana; de Vries, Renko.

In: Analytical Chemistry, Vol. 89, No. 23, 05.12.2017, p. 12812-12820.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Zheng T, Martinez FP, Storm IM, Rombouts W, Sprakel J, Schirhagl R et al. Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors. Analytical Chemistry. 2017 Dec 5;89(23):12812-12820. https://doi.org/10.1021/acs.analchem.7b03236


BibTeX

@article{4ceef92f4294488b898317c1c5b97933,
title = "Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors",
abstract = "Fluorescent nanodiamonds are gaining increasing attention as fluorescent labels in biology in view of the fact that they are essentially nontoxic, do not bleach, and can be used as nanoscale sensors for various physical and chemical properties. To fully realize the nanosensing potential of nanodiamonds in biological applications, two problems need to be addressed: their limited colloidal stability, especially in the presence of salts, and their limited ability to be taken up by cells. We show that the physical adsorption of a suitably designed recombinant polypeptide can address both the colloidal stability problem and the problem of the limited uptake of nanodiamonds by cells in a very straightforward way, while preserving both their spectroscopic properties and their excellent bio compatibility.",
keywords = "NITROGEN-VACANCY CENTERS, FLUORESCENT NANODIAMONDS, MAGNETIC-RESONANCE, OPTICAL MICROSCOPY, CELLS, INTERNALIZATION, POLYGLYCEROL, SPIN, DRUG",
author = "Tingting Zheng and Martinez, {Felipe Perona} and Storm, {Ingeborg Maria} and Wolf Rombouts and Joris Sprakel and Romana Schirhagl and {de Vries}, Renko",
year = "2017",
month = "12",
day = "5",
doi = "10.1021/acs.analchem.7b03236",
language = "English",
volume = "89",
pages = "12812--12820",
journal = "Analytical Chemistry",
issn = "0003-2700",
publisher = "AMER CHEMICAL SOC INC",
number = "23",

}

RIS

TY - JOUR

T1 - Recombinant Protein Polymers for Colloidal Stabilization and Improvement of Cellular Uptake of Diamond Nanosensors

AU - Zheng, Tingting

AU - Martinez, Felipe Perona

AU - Storm, Ingeborg Maria

AU - Rombouts, Wolf

AU - Sprakel, Joris

AU - Schirhagl, Romana

AU - de Vries, Renko

PY - 2017/12/5

Y1 - 2017/12/5

N2 - Fluorescent nanodiamonds are gaining increasing attention as fluorescent labels in biology in view of the fact that they are essentially nontoxic, do not bleach, and can be used as nanoscale sensors for various physical and chemical properties. To fully realize the nanosensing potential of nanodiamonds in biological applications, two problems need to be addressed: their limited colloidal stability, especially in the presence of salts, and their limited ability to be taken up by cells. We show that the physical adsorption of a suitably designed recombinant polypeptide can address both the colloidal stability problem and the problem of the limited uptake of nanodiamonds by cells in a very straightforward way, while preserving both their spectroscopic properties and their excellent bio compatibility.

AB - Fluorescent nanodiamonds are gaining increasing attention as fluorescent labels in biology in view of the fact that they are essentially nontoxic, do not bleach, and can be used as nanoscale sensors for various physical and chemical properties. To fully realize the nanosensing potential of nanodiamonds in biological applications, two problems need to be addressed: their limited colloidal stability, especially in the presence of salts, and their limited ability to be taken up by cells. We show that the physical adsorption of a suitably designed recombinant polypeptide can address both the colloidal stability problem and the problem of the limited uptake of nanodiamonds by cells in a very straightforward way, while preserving both their spectroscopic properties and their excellent bio compatibility.

KW - NITROGEN-VACANCY CENTERS

KW - FLUORESCENT NANODIAMONDS

KW - MAGNETIC-RESONANCE

KW - OPTICAL MICROSCOPY

KW - CELLS

KW - INTERNALIZATION

KW - POLYGLYCEROL

KW - SPIN

KW - DRUG

U2 - 10.1021/acs.analchem.7b03236

DO - 10.1021/acs.analchem.7b03236

M3 - Article

VL - 89

SP - 12812

EP - 12820

JO - Analytical Chemistry

JF - Analytical Chemistry

SN - 0003-2700

IS - 23

ER -

ID: 49888137